The Ribosomal Database Project (RDP) provides a comprehensive database of aligned and annotated rRNA gene sequences, along with tools for analyzing rRNA sequences. The RDP database includes bacterial and archaeal small subunit (SSU) rRNA sequences, as well as fungal large subunit (LSU) rRNA sequences. The database is updated regularly and includes tools such as Classifier and Aligner for rRNA analysis. The RDP also offers tools for browsing and searching the data, taxonomic classification, primer-probe testing, and tree building. Additionally, RDP provides tools for processing high-throughput amplicon sequence data, including RDPipeline, which is designed for high-volume sequencing projects. The RDP also includes tools for ecological analysis, such as calculating alpha and beta diversity, and for sequence quality checks. The RDP offers a variety of tools for sequence analysis, including SeqMatch, Probe Match, and the RDP Aligner. The RDP also provides a user-friendly interface for accessing and analyzing data, including myRDP, which allows researchers to upload and store their sequences. The RDP is a valuable resource for researchers in fields such as human health, microbial ecology, environmental microbiology, nucleic acid chemistry, taxonomy, and phylogenetics. The RDP is available as open-source software and provides a range of tools for rRNA analysis, including the RDP Classifier, which is used for taxonomic classification of rRNA sequences. The RDP also includes a variety of tools for sequence comparison, clustering, and ecological analysis. The RDP is an essential resource for researchers working with rRNA sequences and provides a comprehensive set of tools for analyzing and interpreting rRNA data.The Ribosomal Database Project (RDP) provides a comprehensive database of aligned and annotated rRNA gene sequences, along with tools for analyzing rRNA sequences. The RDP database includes bacterial and archaeal small subunit (SSU) rRNA sequences, as well as fungal large subunit (LSU) rRNA sequences. The database is updated regularly and includes tools such as Classifier and Aligner for rRNA analysis. The RDP also offers tools for browsing and searching the data, taxonomic classification, primer-probe testing, and tree building. Additionally, RDP provides tools for processing high-throughput amplicon sequence data, including RDPipeline, which is designed for high-volume sequencing projects. The RDP also includes tools for ecological analysis, such as calculating alpha and beta diversity, and for sequence quality checks. The RDP offers a variety of tools for sequence analysis, including SeqMatch, Probe Match, and the RDP Aligner. The RDP also provides a user-friendly interface for accessing and analyzing data, including myRDP, which allows researchers to upload and store their sequences. The RDP is a valuable resource for researchers in fields such as human health, microbial ecology, environmental microbiology, nucleic acid chemistry, taxonomy, and phylogenetics. The RDP is available as open-source software and provides a range of tools for rRNA analysis, including the RDP Classifier, which is used for taxonomic classification of rRNA sequences. The RDP also includes a variety of tools for sequence comparison, clustering, and ecological analysis. The RDP is an essential resource for researchers working with rRNA sequences and provides a comprehensive set of tools for analyzing and interpreting rRNA data.