2024 | Ugur Bozuyuk, Paul Wrede, Erdost Yildiz, and Metin Sitti*
The article "Roadmap for Clinical Translation of Mobile Microrobotics" by Ugur Bozuyuk, Paul Wrede, Erdost Yildiz, and Metin Sitti discusses the challenges and potential of medical microrobotics in clinical applications. The authors highlight the importance of collaboration between clinical experts and microrobotics researchers to address technical challenges such as microfabrication, safety, and imaging. They emphasize the need for designing microrobots that can overcome limitations in actuation, material stability, and imaging constraints. The article also reviews the current status of medical microrobotics, including the development of novel actuation mechanisms and advanced fabrication techniques. It outlines the physical and biological constraints of microrobotics in the human body, such as fluid dynamics, tissue interactions, and immune responses. Additionally, the article discusses the importance of biocompatibility, targeting strategies, and biodistribution in the clinical translation of medical microrobots. The authors provide a roadmap for future research, emphasizing the need for comprehensive testing and validation in physiological settings to ensure the safety and effectiveness of these devices in clinical settings.The article "Roadmap for Clinical Translation of Mobile Microrobotics" by Ugur Bozuyuk, Paul Wrede, Erdost Yildiz, and Metin Sitti discusses the challenges and potential of medical microrobotics in clinical applications. The authors highlight the importance of collaboration between clinical experts and microrobotics researchers to address technical challenges such as microfabrication, safety, and imaging. They emphasize the need for designing microrobots that can overcome limitations in actuation, material stability, and imaging constraints. The article also reviews the current status of medical microrobotics, including the development of novel actuation mechanisms and advanced fabrication techniques. It outlines the physical and biological constraints of microrobotics in the human body, such as fluid dynamics, tissue interactions, and immune responses. Additionally, the article discusses the importance of biocompatibility, targeting strategies, and biodistribution in the clinical translation of medical microrobots. The authors provide a roadmap for future research, emphasizing the need for comprehensive testing and validation in physiological settings to ensure the safety and effectiveness of these devices in clinical settings.