This paper presents a clinical trial evaluating the effectiveness of robot-aided therapy in neurorehabilitation for stroke patients. The study involved 20 patients with hemiparesis due to a cerebral vascular accident. The MIT-MANUS robot was used to assist in therapy, and kinematic data were collected to analyze movement patterns. The results showed that robot-aided therapy had no adverse effects, was well tolerated by patients, and that manipulation of the impaired limb may influence brain recovery. The study also demonstrated that patients in the robot-aided therapy group improved more significantly in motor function assessments compared to the control group. The robot-aided therapy group showed better recovery in shoulder and elbow function, as well as improved Fugl-Meyer and motor power scores. The study suggests that robot-aided therapy could be a promising tool for neurological rehabilitation, offering the potential for more effective and objective assessment of recovery. The findings indicate that robot-aided therapy may enhance motor recovery and provide a more structured and quantifiable approach to neurorehabilitation. The study also highlights the importance of kinematic analysis in understanding the recovery process and the potential for future research to tailor therapy to individual patient needs. The results suggest that robot-aided therapy could lead to more efficient and effective rehabilitation strategies, potentially reducing costs and improving patient outcomes.This paper presents a clinical trial evaluating the effectiveness of robot-aided therapy in neurorehabilitation for stroke patients. The study involved 20 patients with hemiparesis due to a cerebral vascular accident. The MIT-MANUS robot was used to assist in therapy, and kinematic data were collected to analyze movement patterns. The results showed that robot-aided therapy had no adverse effects, was well tolerated by patients, and that manipulation of the impaired limb may influence brain recovery. The study also demonstrated that patients in the robot-aided therapy group improved more significantly in motor function assessments compared to the control group. The robot-aided therapy group showed better recovery in shoulder and elbow function, as well as improved Fugl-Meyer and motor power scores. The study suggests that robot-aided therapy could be a promising tool for neurological rehabilitation, offering the potential for more effective and objective assessment of recovery. The findings indicate that robot-aided therapy may enhance motor recovery and provide a more structured and quantifiable approach to neurorehabilitation. The study also highlights the importance of kinematic analysis in understanding the recovery process and the potential for future research to tailor therapy to individual patient needs. The results suggest that robot-aided therapy could lead to more efficient and effective rehabilitation strategies, potentially reducing costs and improving patient outcomes.