13 March 2024 | Jason M. Kronenfeld1, Lukas Rother2, Max A. Saccone3, Maria T. Dulay2 & Joseph M. DeSimone2,5
This paper introduces a scalable, high-resolution 3D printing technique called roll-to-roll continuous liquid interface production (r2CLIP) for fabricating shape-specific particles. The technique uses single-digit micron-resolution optics and a continuous roll of film to rapidly produce and harvest particles with complex geometries from various materials. r2CLIP can create particles with voxel sizes as small as 2.0 × 2.0 μm³ and unsupported thicknesses of 1.1 ± 0.3 μm, at speeds of up to 1,000,000 particles per day. The method is versatile, enabling the fabrication of both moldable and non-moldable shapes, and has potential applications in biomedical devices, drug delivery systems, microelectronics, and energy storage systems. The paper also discusses the advantages of r2CLIP over traditional particle fabrication methods, such as bottom-up and top-down approaches, and highlights its ability to produce particles with intricate designs that can be directly integrated into advanced applications.This paper introduces a scalable, high-resolution 3D printing technique called roll-to-roll continuous liquid interface production (r2CLIP) for fabricating shape-specific particles. The technique uses single-digit micron-resolution optics and a continuous roll of film to rapidly produce and harvest particles with complex geometries from various materials. r2CLIP can create particles with voxel sizes as small as 2.0 × 2.0 μm³ and unsupported thicknesses of 1.1 ± 0.3 μm, at speeds of up to 1,000,000 particles per day. The method is versatile, enabling the fabrication of both moldable and non-moldable shapes, and has potential applications in biomedical devices, drug delivery systems, microelectronics, and energy storage systems. The paper also discusses the advantages of r2CLIP over traditional particle fabrication methods, such as bottom-up and top-down approaches, and highlights its ability to produce particles with intricate designs that can be directly integrated into advanced applications.