This study demonstrates room-temperature strong coupling between a single-photon emitter (SPE) and a bound-state-in-the-continuum (BIC) cavity. The SPEs are carbon-based color centers in hexagonal boron nitride (hBN), known for their high brightness and long coherence time. The BIC cavity, formed by a TiO₂ nanopillar array, ensures perfect photon trapping and reduces the coupling loss. Experimentally, a Rabi splitting of approximately 4 meV was observed at room temperature, indicating strong coupling. This achievement opens new avenues for scalable quantum devices operating at ambient conditions, leveraging the unique properties of hBN SPEs and the robustness of BIC cavities. The findings highlight the potential for advanced quantum technologies, including quantum information processing and spin-photon interfaces.This study demonstrates room-temperature strong coupling between a single-photon emitter (SPE) and a bound-state-in-the-continuum (BIC) cavity. The SPEs are carbon-based color centers in hexagonal boron nitride (hBN), known for their high brightness and long coherence time. The BIC cavity, formed by a TiO₂ nanopillar array, ensures perfect photon trapping and reduces the coupling loss. Experimentally, a Rabi splitting of approximately 4 meV was observed at room temperature, indicating strong coupling. This achievement opens new avenues for scalable quantum devices operating at ambient conditions, leveraging the unique properties of hBN SPEs and the robustness of BIC cavities. The findings highlight the potential for advanced quantum technologies, including quantum information processing and spin-photon interfaces.