2008 November ; 11(6): 693–700 | Sari Stenholm, PhD1,2, Tamara B. Harris, MD, MS3, Taina Rantanen, PhD4, Marjolein Visser, PhD5, Stephen B. Kritchevsky, PhD6, and Luigi Ferrucci, MD, PhD1
The article reviews the concept of "sarcopenic obesity," which refers to older individuals who are obese and have decreased muscle mass or strength. It discusses the potential pathways leading to muscle impairment in obese individuals, including excess energy intake, physical inactivity, low-grade inflammation, insulin resistance, and hormonal changes. The authors argue that the risk of adverse outcomes such as functional limitation and mortality is better estimated by considering both obesity and muscle strength together rather than just obesity and muscle mass. They propose that the term "sarcopenic obesity" should be revisited and that further research is needed to identify new targets for prevention and treatment of this geriatric syndrome. The article also highlights the importance of recognizing obese patients with associated muscle problems and the need for collaboration between researchers in different fields to advance understanding and management of this condition.The article reviews the concept of "sarcopenic obesity," which refers to older individuals who are obese and have decreased muscle mass or strength. It discusses the potential pathways leading to muscle impairment in obese individuals, including excess energy intake, physical inactivity, low-grade inflammation, insulin resistance, and hormonal changes. The authors argue that the risk of adverse outcomes such as functional limitation and mortality is better estimated by considering both obesity and muscle strength together rather than just obesity and muscle mass. They propose that the term "sarcopenic obesity" should be revisited and that further research is needed to identify new targets for prevention and treatment of this geriatric syndrome. The article also highlights the importance of recognizing obese patients with associated muscle problems and the need for collaboration between researchers in different fields to advance understanding and management of this condition.