The article discusses the importance of self-management (SM) in cancer care as a chronic illness. With advancements in cancer detection and treatment, patients are living longer and managing cancer as a chronic condition. This requires patients and families to take an active role in managing their care, challenging traditional models of care. The Chronic Care Model (CCM) is presented as a framework to support SM, enabling patients and families to engage in self-management across the cancer care continuum. The article reviews evidence from randomized controlled trials showing that SM interventions improve patient outcomes in treatment, survivorship, and end-of-life phases. Key components of SM include managing medical, role, and emotional aspects of illness, along with skills like problem-solving and decision-making. Studies show that SM interventions can reduce symptom severity, improve quality of life, and enhance patient confidence. The CCM emphasizes the need for patient-provider partnerships, shared decision-making, and ongoing support to enable patients to manage their care. The article concludes that oncology practices can now implement SM interventions to empower patients and families to care for themselves in the way they prefer.The article discusses the importance of self-management (SM) in cancer care as a chronic illness. With advancements in cancer detection and treatment, patients are living longer and managing cancer as a chronic condition. This requires patients and families to take an active role in managing their care, challenging traditional models of care. The Chronic Care Model (CCM) is presented as a framework to support SM, enabling patients and families to engage in self-management across the cancer care continuum. The article reviews evidence from randomized controlled trials showing that SM interventions improve patient outcomes in treatment, survivorship, and end-of-life phases. Key components of SM include managing medical, role, and emotional aspects of illness, along with skills like problem-solving and decision-making. Studies show that SM interventions can reduce symptom severity, improve quality of life, and enhance patient confidence. The CCM emphasizes the need for patient-provider partnerships, shared decision-making, and ongoing support to enable patients to manage their care. The article concludes that oncology practices can now implement SM interventions to empower patients and families to care for themselves in the way they prefer.