The article "Self-Assembled Nanoreactors" by Vriezema et al. provides an overview of synthetic and biological nanoreactors constructed from molecular and macromolecular building blocks. The primary focus is on self-assembled systems, ranging from a few nanometers to tens of micrometers in size. These nanoreactors mimic the confined environments found in nature, where chemical reactions are tightly coupled in time and space, enhancing efficiency and selectivity. The review is divided into several sections, covering the development of tailor-made nanoreactors, including capsules, micelles, and vesicles. Covalent and noncovalent approaches are discussed, with a particular emphasis on self-assembly through hydrogen bonding and metal-ligand interactions. Examples of artificial enzymes and catalysts are provided, highlighting their efficiency and selectivity. The article also explores the use of viruses as nanocontainers and reactors, and the application of nanoreactors in various chemical reactions, such as Diels-Alder reactions and phase-transfer catalysis. Key findings include the development of self-assembled capsules that can function as microreactors, accelerating and controlling chemical reactions. The encapsulation of catalysts within these capsules enhances their stability and activity, leading to improved reaction outcomes. Additionally, the article discusses the use of nanoreactors in more sophisticated processes, such as chemical amplification and dynamic combinatorial libraries, demonstrating their potential for advanced chemical applications.The article "Self-Assembled Nanoreactors" by Vriezema et al. provides an overview of synthetic and biological nanoreactors constructed from molecular and macromolecular building blocks. The primary focus is on self-assembled systems, ranging from a few nanometers to tens of micrometers in size. These nanoreactors mimic the confined environments found in nature, where chemical reactions are tightly coupled in time and space, enhancing efficiency and selectivity. The review is divided into several sections, covering the development of tailor-made nanoreactors, including capsules, micelles, and vesicles. Covalent and noncovalent approaches are discussed, with a particular emphasis on self-assembly through hydrogen bonding and metal-ligand interactions. Examples of artificial enzymes and catalysts are provided, highlighting their efficiency and selectivity. The article also explores the use of viruses as nanocontainers and reactors, and the application of nanoreactors in various chemical reactions, such as Diels-Alder reactions and phase-transfer catalysis. Key findings include the development of self-assembled capsules that can function as microreactors, accelerating and controlling chemical reactions. The encapsulation of catalysts within these capsules enhances their stability and activity, leading to improved reaction outcomes. Additionally, the article discusses the use of nanoreactors in more sophisticated processes, such as chemical amplification and dynamic combinatorial libraries, demonstrating their potential for advanced chemical applications.