Serratia spp. are plant growth-promoting bacteria that alleviate salinity, drought, and nutrient imbalance stresses. This mini-review summarizes current knowledge on how Serratia spp. promote plant growth under these conditions and highlights areas for further research. Serratia spp. strains exhibit various traits that enhance plant growth and stress tolerance, including phytohormone production, ACC deaminase activity, nitrogen fixation, P and Zn solubilization, antioxidant properties, and gene expression modulation. However, further research is needed to elucidate the molecular mechanisms of action and the effects of Serratia spp. on indigenous soil and plant microbiota, particularly the rhizosphere. Additionally, some Serratia spp. strains may be phytopathogens, so studies to rule this out are recommended before field trials. The potential of Serratia spp. as eco-friendly biofertilizers in sustainable agriculture is significant, but more research is needed to fully understand their mechanisms and applications. Serratia spp. have been shown to alleviate salinity and drought stress by mechanisms such as ACC deaminase production, EPS production, and osmolyte production. They also improve plant growth by enhancing nutrient uptake and inducing osmolyte and antioxidant accumulation. However, the biochemical and molecular mechanisms governing drought stress resistance induced by Serratia spp. are still unclear, and further research using omics approaches is needed. Serratia spp. also show potential in mitigating drought stress by producing ACC deaminase, EPS, and various phytohormones. The review concludes that Serratia spp. have significant potential as plant growth-promoting bacteria in sustainable agriculture, but further research is needed to fully realize their potential.Serratia spp. are plant growth-promoting bacteria that alleviate salinity, drought, and nutrient imbalance stresses. This mini-review summarizes current knowledge on how Serratia spp. promote plant growth under these conditions and highlights areas for further research. Serratia spp. strains exhibit various traits that enhance plant growth and stress tolerance, including phytohormone production, ACC deaminase activity, nitrogen fixation, P and Zn solubilization, antioxidant properties, and gene expression modulation. However, further research is needed to elucidate the molecular mechanisms of action and the effects of Serratia spp. on indigenous soil and plant microbiota, particularly the rhizosphere. Additionally, some Serratia spp. strains may be phytopathogens, so studies to rule this out are recommended before field trials. The potential of Serratia spp. as eco-friendly biofertilizers in sustainable agriculture is significant, but more research is needed to fully understand their mechanisms and applications. Serratia spp. have been shown to alleviate salinity and drought stress by mechanisms such as ACC deaminase production, EPS production, and osmolyte production. They also improve plant growth by enhancing nutrient uptake and inducing osmolyte and antioxidant accumulation. However, the biochemical and molecular mechanisms governing drought stress resistance induced by Serratia spp. are still unclear, and further research using omics approaches is needed. Serratia spp. also show potential in mitigating drought stress by producing ACC deaminase, EPS, and various phytohormones. The review concludes that Serratia spp. have significant potential as plant growth-promoting bacteria in sustainable agriculture, but further research is needed to fully realize their potential.