1988;41:467–470 | T ASHCROFT, JUDY M SIMPSON, V TIMBRELL
The article presents a method for quantifying the severity of pulmonary fibrosis using a continuous numerical scale from 0 to 8. This scale is designed to correlate with other pulmonary variables such as lung function tests or mineral burden. The scoring system is based on microscopic examination of lung tissue sections, where each field is assessed for the degree of interstitial fibrosis and given a score. The mean score of all fields in a section is used as the final fibrosis score. The method allows for detailed measurement of fibrosis in small tissue samples (1 cm), which is not possible with most existing methods. The study also assesses the intraobserver and interobserver variability of the scoring system, showing good repeatability and significant interobserver variation. The authors conclude that their method is suitable for a wide range of fibrosing pulmonary conditions, including non-occupational diseases like idiopathic fibrosing alveolitis.The article presents a method for quantifying the severity of pulmonary fibrosis using a continuous numerical scale from 0 to 8. This scale is designed to correlate with other pulmonary variables such as lung function tests or mineral burden. The scoring system is based on microscopic examination of lung tissue sections, where each field is assessed for the degree of interstitial fibrosis and given a score. The mean score of all fields in a section is used as the final fibrosis score. The method allows for detailed measurement of fibrosis in small tissue samples (1 cm), which is not possible with most existing methods. The study also assesses the intraobserver and interobserver variability of the scoring system, showing good repeatability and significant interobserver variation. The authors conclude that their method is suitable for a wide range of fibrosing pulmonary conditions, including non-occupational diseases like idiopathic fibrosing alveolitis.