This article presents a novel organic cage-based humidity sensor with exceptional humidity responsiveness, forming the basis for advanced touchless human-machine interaction (HMI) systems. The sensor, named Cage-1, features a 3D crystal structure with abundant water-absorbing functional groups, enabling ultrafast response/recovery times (1 s/3 s) and remarkable stability (over 800 cycles) across relative humidity (RH) changes from 11% to 95%. The sensor's performance is attributed to its self-assembled 3D water channels and extensive hydrogen bonding sites, which facilitate efficient water transfer and proton conduction. The sensor's unique structure allows it to respond rapidly to changes in humidity, making it highly suitable for touchless HMI applications. The study compares the performance of Cage-1 with two other materials: Cage-2 (lacking carboxyl groups) and a common 2D trianglamine macrocycle (TA). Results show that Cage-1 exhibits significantly better humidity sensing properties, including faster response and recovery times, higher proton conductivity, and superior cycle stability. The sensor's high crystallinity and porosity enable efficient water diffusion and sensing, making it ideal for touchless applications such as smart control screens and touchless password managers. The sensor's performance was tested under various humidity conditions, demonstrating its ability to detect changes in humidity levels with high accuracy. The sensor's response to humidity was also evaluated in real-world scenarios, showing consistent performance and reliability. The study further demonstrates the sensor's potential for detecting human respiratory behavior, as it can detect water vapor molecules in exhaled air, leading to changes in resistance signals. The sensor's design and performance highlight the potential of molecularly porous materials in touchless HMI applications. The study also discusses the advantages of the sensor's structure, including its high porosity, interconnected water channels, and efficient proton conduction. These features contribute to the sensor's rapid response and high stability, making it a promising candidate for future touchless HMI systems. The study concludes that the Cage-1 humidity sensor represents a significant advancement in touchless HMI technology, offering a cost-effective and easily processable solution for humidity sensing.This article presents a novel organic cage-based humidity sensor with exceptional humidity responsiveness, forming the basis for advanced touchless human-machine interaction (HMI) systems. The sensor, named Cage-1, features a 3D crystal structure with abundant water-absorbing functional groups, enabling ultrafast response/recovery times (1 s/3 s) and remarkable stability (over 800 cycles) across relative humidity (RH) changes from 11% to 95%. The sensor's performance is attributed to its self-assembled 3D water channels and extensive hydrogen bonding sites, which facilitate efficient water transfer and proton conduction. The sensor's unique structure allows it to respond rapidly to changes in humidity, making it highly suitable for touchless HMI applications. The study compares the performance of Cage-1 with two other materials: Cage-2 (lacking carboxyl groups) and a common 2D trianglamine macrocycle (TA). Results show that Cage-1 exhibits significantly better humidity sensing properties, including faster response and recovery times, higher proton conductivity, and superior cycle stability. The sensor's high crystallinity and porosity enable efficient water diffusion and sensing, making it ideal for touchless applications such as smart control screens and touchless password managers. The sensor's performance was tested under various humidity conditions, demonstrating its ability to detect changes in humidity levels with high accuracy. The sensor's response to humidity was also evaluated in real-world scenarios, showing consistent performance and reliability. The study further demonstrates the sensor's potential for detecting human respiratory behavior, as it can detect water vapor molecules in exhaled air, leading to changes in resistance signals. The sensor's design and performance highlight the potential of molecularly porous materials in touchless HMI applications. The study also discusses the advantages of the sensor's structure, including its high porosity, interconnected water channels, and efficient proton conduction. These features contribute to the sensor's rapid response and high stability, making it a promising candidate for future touchless HMI systems. The study concludes that the Cage-1 humidity sensor represents a significant advancement in touchless HMI technology, offering a cost-effective and easily processable solution for humidity sensing.