The study examines the sociodemographic and health-related factors associated with current adult social media users in the United States, using data from the 2007 Health Information National Trends Survey (HINTS). The survey found that approximately 69% of US adults had internet access, with 5% participating in online support groups, 7% blogging, and 23% using social networking sites. Multivariate analysis revealed that younger age was the only significant predictor of blogging and social networking site participation, with a statistically significant linear relationship observed. Younger age, poorer subjective health, and a personal cancer experience predicted support group participation. Social media use was generally independent of education, race/ethnicity, or healthcare access. The findings suggest that health communication programs utilizing social media should consider the age of the targeted population to ensure messages reach the intended audience. While racial/ethnic and health status disparities exist in internet access, these characteristics do not affect social media use, indicating that social media may be changing communication patterns across the US population.The study examines the sociodemographic and health-related factors associated with current adult social media users in the United States, using data from the 2007 Health Information National Trends Survey (HINTS). The survey found that approximately 69% of US adults had internet access, with 5% participating in online support groups, 7% blogging, and 23% using social networking sites. Multivariate analysis revealed that younger age was the only significant predictor of blogging and social networking site participation, with a statistically significant linear relationship observed. Younger age, poorer subjective health, and a personal cancer experience predicted support group participation. Social media use was generally independent of education, race/ethnicity, or healthcare access. The findings suggest that health communication programs utilizing social media should consider the age of the targeted population to ensure messages reach the intended audience. While racial/ethnic and health status disparities exist in internet access, these characteristics do not affect social media use, indicating that social media may be changing communication patterns across the US population.