Soil salinization is a critical threat to agriculture and food security, caused by natural and human factors, including climate change, poor irrigation, and excessive fertilizer use. It negatively affects soil structure, fertility, and crop yields. Nature-based solutions (NBS) and bioengineering are proposed as sustainable strategies to mitigate salinization. NBS, such as mangrove restoration, wetland conservation, and buffer zones, help combat salinity by restoring ecosystems and improving water management. However, their effectiveness depends on local conditions and may face challenges like land tenure issues and high costs. Bioengineering offers the potential to develop salt-tolerant crops, which can complement NBS in vulnerable regions. Combining NBS with salt-tolerant crops is essential to achieve the Sustainable Development Goal of Zero Hunger (SDG2). Strategies such as straw incorporation, microbial-based solutions, organic fertilizers, and crop rotation are also effective in reducing salinization. Additionally, water management practices like rainwater harvesting and precision irrigation are crucial. Breeding for salt tolerance in crops is another promising approach, supported by advances in genomics and gene editing. These integrated strategies are necessary to address the growing threat of soil salinization and ensure food security in delta regions and arid areas. The combination of NBS and bioengineering can provide a sustainable solution to mitigate salinization and support agricultural productivity in the face of climate change.Soil salinization is a critical threat to agriculture and food security, caused by natural and human factors, including climate change, poor irrigation, and excessive fertilizer use. It negatively affects soil structure, fertility, and crop yields. Nature-based solutions (NBS) and bioengineering are proposed as sustainable strategies to mitigate salinization. NBS, such as mangrove restoration, wetland conservation, and buffer zones, help combat salinity by restoring ecosystems and improving water management. However, their effectiveness depends on local conditions and may face challenges like land tenure issues and high costs. Bioengineering offers the potential to develop salt-tolerant crops, which can complement NBS in vulnerable regions. Combining NBS with salt-tolerant crops is essential to achieve the Sustainable Development Goal of Zero Hunger (SDG2). Strategies such as straw incorporation, microbial-based solutions, organic fertilizers, and crop rotation are also effective in reducing salinization. Additionally, water management practices like rainwater harvesting and precision irrigation are crucial. Breeding for salt tolerance in crops is another promising approach, supported by advances in genomics and gene editing. These integrated strategies are necessary to address the growing threat of soil salinization and ensure food security in delta regions and arid areas. The combination of NBS and bioengineering can provide a sustainable solution to mitigate salinization and support agricultural productivity in the face of climate change.