This study examines the relationship between stigma and help-seeking behavior among college students, using a random sample of 5,555 students from 13 diverse universities. The main findings are: 1. **Perceived Public Stigma vs. Personal Stigma**: Perceived public stigma was significantly higher than personal stigma. 2. **Characteristics Associated with Personal Stigma**: Personal stigma was higher among male students, younger students, Asian students, international students, more religious students, and those from poor families. 3. **Association with Help-Seeking Behavior**: Personal stigma was significantly associated with lower help-seeking behavior (perceived need for help, use of psychotropic medication, therapy, and nonclinical support), while perceived stigma was not significantly associated with help-seeking behavior. The study suggests that reducing personal stigma, rather than perceived public stigma, may be more effective in increasing help-seeking behavior among college students. The findings highlight the need for targeted stigma reduction efforts, such as education and social contact programs, to address the specific attitudes and behaviors of different student populations.This study examines the relationship between stigma and help-seeking behavior among college students, using a random sample of 5,555 students from 13 diverse universities. The main findings are: 1. **Perceived Public Stigma vs. Personal Stigma**: Perceived public stigma was significantly higher than personal stigma. 2. **Characteristics Associated with Personal Stigma**: Personal stigma was higher among male students, younger students, Asian students, international students, more religious students, and those from poor families. 3. **Association with Help-Seeking Behavior**: Personal stigma was significantly associated with lower help-seeking behavior (perceived need for help, use of psychotropic medication, therapy, and nonclinical support), while perceived stigma was not significantly associated with help-seeking behavior. The study suggests that reducing personal stigma, rather than perceived public stigma, may be more effective in increasing help-seeking behavior among college students. The findings highlight the need for targeted stigma reduction efforts, such as education and social contact programs, to address the specific attitudes and behaviors of different student populations.