Superhydrophobic surfaces (SHS) have been widely studied for their ability to minimize the water/solid contact interface, allowing water droplets to retain spherical shapes and roll off easily. These properties make SHS suitable for fabricating microspheres and supraparticles, which have various applications in photonic devices, catalysts, and biomedical fields. This review summarizes the strategies for fabricating microspheres and supraparticles using SHS, including cross-linking curing, polymer melting, and droplet template evaporation methods. The applications of these materials in photonic devices with tunable structural colors, catalysts with emerging properties, and biomedical applications such as drug delivery and protein crystallization are discussed. The review also highlights the challenges and future prospects of this research field. The SHS-assisted fabrication strategies offer advantages such as material saving, reduced organic pollution, and high throughput production. The review discusses the fabrication of microspheres and supraparticles through various methods, including cross-linking curing, polymer melting, and droplet template evaporation. The applications of these materials in photonic devices, catalysts, and biomedical fields are detailed, along with the challenges and future directions of this research. The review concludes with a discussion of the potential of SHS-assisted fabrication strategies for creating microspheres and supraparticles with tunable properties and applications.Superhydrophobic surfaces (SHS) have been widely studied for their ability to minimize the water/solid contact interface, allowing water droplets to retain spherical shapes and roll off easily. These properties make SHS suitable for fabricating microspheres and supraparticles, which have various applications in photonic devices, catalysts, and biomedical fields. This review summarizes the strategies for fabricating microspheres and supraparticles using SHS, including cross-linking curing, polymer melting, and droplet template evaporation methods. The applications of these materials in photonic devices with tunable structural colors, catalysts with emerging properties, and biomedical applications such as drug delivery and protein crystallization are discussed. The review also highlights the challenges and future prospects of this research field. The SHS-assisted fabrication strategies offer advantages such as material saving, reduced organic pollution, and high throughput production. The review discusses the fabrication of microspheres and supraparticles through various methods, including cross-linking curing, polymer melting, and droplet template evaporation. The applications of these materials in photonic devices, catalysts, and biomedical fields are detailed, along with the challenges and future directions of this research. The review concludes with a discussion of the potential of SHS-assisted fabrication strategies for creating microspheres and supraparticles with tunable properties and applications.