The supplemental material provides additional data and analysis supporting the main findings of the study. Figure S1 shows that Atg5-deficient chimeras have significantly reduced survival compared to Atg5野生型 chimeras, with a p-value indicating statistical significance. Figure S2 demonstrates the recombination of the Atg5flx allele in Atg5F/F Cre+ thymocytes through PCR analysis. Supplemental Figure 3 includes two heatmaps: (A) mitochondrial functions and (B) general cellular processes or specific T-lineage immune functions, generated from literature co-citation analysis of differentially expressed genes. The intensity of red in the heatmaps indicates the extent to which each gene is co-cited with specific terms in the PubMed database.The supplemental material provides additional data and analysis supporting the main findings of the study. Figure S1 shows that Atg5-deficient chimeras have significantly reduced survival compared to Atg5野生型 chimeras, with a p-value indicating statistical significance. Figure S2 demonstrates the recombination of the Atg5flx allele in Atg5F/F Cre+ thymocytes through PCR analysis. Supplemental Figure 3 includes two heatmaps: (A) mitochondrial functions and (B) general cellular processes or specific T-lineage immune functions, generated from literature co-citation analysis of differentially expressed genes. The intensity of red in the heatmaps indicates the extent to which each gene is co-cited with specific terms in the PubMed database.