The integration of sustainability and ethics in supply chain management is critical for modern organizations aiming to align with environmental and social responsibilities. This review paper synthesizes existing research and practices to propose a comprehensive strategy for sustainable and ethical supply chain management. A systematic literature review of over 150 peer-reviewed articles and industry reports highlights key themes, challenges, and successful practices in the field. The paper identifies transparency, traceability, and collaboration as essential elements driving ethical and sustainable practices. Technological advancements such as blockchain and AI are discussed as tools that enhance these practices. The conclusion emphasizes that integrating sustainability and ethics mitigates risks, improves compliance, and provides competitive advantages through innovation and market positioning. The paper recommends a strategic framework including policy development, training programs, and technology adoption to foster a culture of sustainability. It also underscores the importance of ethical practices in supply chains, noting their role in building trust, enhancing performance, and aligning with global regulations. The review highlights the significance of sustainability and ethics in shaping modern supply chains, emphasizing the need for transparency, responsibility, and strategic integration to achieve long-term success. The study concludes that sustainable and ethical practices are not only essential for compliance but also serve as drivers of innovation and competitive advantage in supply chain management.The integration of sustainability and ethics in supply chain management is critical for modern organizations aiming to align with environmental and social responsibilities. This review paper synthesizes existing research and practices to propose a comprehensive strategy for sustainable and ethical supply chain management. A systematic literature review of over 150 peer-reviewed articles and industry reports highlights key themes, challenges, and successful practices in the field. The paper identifies transparency, traceability, and collaboration as essential elements driving ethical and sustainable practices. Technological advancements such as blockchain and AI are discussed as tools that enhance these practices. The conclusion emphasizes that integrating sustainability and ethics mitigates risks, improves compliance, and provides competitive advantages through innovation and market positioning. The paper recommends a strategic framework including policy development, training programs, and technology adoption to foster a culture of sustainability. It also underscores the importance of ethical practices in supply chains, noting their role in building trust, enhancing performance, and aligning with global regulations. The review highlights the significance of sustainability and ethics in shaping modern supply chains, emphasizing the need for transparency, responsibility, and strategic integration to achieve long-term success. The study concludes that sustainable and ethical practices are not only essential for compliance but also serve as drivers of innovation and competitive advantage in supply chain management.