This review paper explores the integration of nanogenerators (NGs) and solar cells (SCs) to develop advanced hybrid structures and their diverse applications. NGs and SCs are promising technologies for energy harvesting from microenergy sources, offering innovative solutions for sustainable energy. The integration of NGs and SCs provides a dual power source, combining solar and mechanical energy harvesting, enhancing energy adaptability and reliability. The review discusses the working mechanisms of various energy harvesters, including piezoelectric (PENG), triboelectric (TENG), pyroelectric (PYNG), and electromagnetic (EMG) nanogenerators, as well as photovoltaic (PV) cells. Advanced hybrid structures, such as DSSC-NG, QDSSC-NG, and SSC-NG, are analyzed, highlighting their performance, challenges, and applications in self-powered electronics, wearable devices, environmental monitoring, and wireless sensor networks. The review also covers the development of flexible hybrid devices, including fabric-based solar cells and nanogenerators, which can harvest energy from solar, wind, and rain. Applications in smart agriculture, such as hybrid energy harvesting systems for agricultural monitoring, are discussed, along with smart sensor applications using TENGs for self-sustaining sensors. The integration of NGs and SCs offers a sustainable and self-sufficient solution for energy needs, contributing to the development of green and energy-efficient technologies. The review emphasizes the potential of hybrid systems to address real-world energy challenges and promote sustainable energy solutions.This review paper explores the integration of nanogenerators (NGs) and solar cells (SCs) to develop advanced hybrid structures and their diverse applications. NGs and SCs are promising technologies for energy harvesting from microenergy sources, offering innovative solutions for sustainable energy. The integration of NGs and SCs provides a dual power source, combining solar and mechanical energy harvesting, enhancing energy adaptability and reliability. The review discusses the working mechanisms of various energy harvesters, including piezoelectric (PENG), triboelectric (TENG), pyroelectric (PYNG), and electromagnetic (EMG) nanogenerators, as well as photovoltaic (PV) cells. Advanced hybrid structures, such as DSSC-NG, QDSSC-NG, and SSC-NG, are analyzed, highlighting their performance, challenges, and applications in self-powered electronics, wearable devices, environmental monitoring, and wireless sensor networks. The review also covers the development of flexible hybrid devices, including fabric-based solar cells and nanogenerators, which can harvest energy from solar, wind, and rain. Applications in smart agriculture, such as hybrid energy harvesting systems for agricultural monitoring, are discussed, along with smart sensor applications using TENGs for self-sustaining sensors. The integration of NGs and SCs offers a sustainable and self-sufficient solution for energy needs, contributing to the development of green and energy-efficient technologies. The review emphasizes the potential of hybrid systems to address real-world energy challenges and promote sustainable energy solutions.