This article explores the role of Information Technology (IT) in enhancing global supply chain resilience. It highlights how IT tools and systems contribute to improving supply chain resilience across various industries and regions. The integration of advanced technologies such as Artificial Intelligence (AI), Internet of Things (IoT), and blockchain is examined, emphasizing their transformative impact on supply chain management. These technologies enable real-time visibility, predictive analytics, and secure information sharing, empowering organizations to proactively identify risks and respond swiftly to disruptions. The review also discusses the significance of digital platforms and cloud-based solutions in fostering collaboration and agility within supply chains. Seamless information sharing among supply chain partners facilitates quick decision-making and adaptive responses to unforeseen challenges. Case studies from various global contexts provide insights into successful IT implementations that have significantly improved supply chain resilience, showcasing best practices and lessons learned. The article emphasizes the critical role of IT in fortifying supply chain resilience, particularly in an era of increasing uncertainties and disruptions. It underscores the importance of IT-driven strategies in building robust, adaptable, and responsive supply chains that can withstand and recover from disruptions effectively. The integration of IT in supply chain management is instrumental in enhancing firm financial performance, customer value, and the design of simulation scenarios. This underscores the critical role of IT in navigating the complexities and risks inherent in global supply chains, ultimately contributing to the resilience and sustainability of supply chain operations.This article explores the role of Information Technology (IT) in enhancing global supply chain resilience. It highlights how IT tools and systems contribute to improving supply chain resilience across various industries and regions. The integration of advanced technologies such as Artificial Intelligence (AI), Internet of Things (IoT), and blockchain is examined, emphasizing their transformative impact on supply chain management. These technologies enable real-time visibility, predictive analytics, and secure information sharing, empowering organizations to proactively identify risks and respond swiftly to disruptions. The review also discusses the significance of digital platforms and cloud-based solutions in fostering collaboration and agility within supply chains. Seamless information sharing among supply chain partners facilitates quick decision-making and adaptive responses to unforeseen challenges. Case studies from various global contexts provide insights into successful IT implementations that have significantly improved supply chain resilience, showcasing best practices and lessons learned. The article emphasizes the critical role of IT in fortifying supply chain resilience, particularly in an era of increasing uncertainties and disruptions. It underscores the importance of IT-driven strategies in building robust, adaptable, and responsive supply chains that can withstand and recover from disruptions effectively. The integration of IT in supply chain management is instrumental in enhancing firm financial performance, customer value, and the design of simulation scenarios. This underscores the critical role of IT in navigating the complexities and risks inherent in global supply chains, ultimately contributing to the resilience and sustainability of supply chain operations.