This perspective discusses the potential of tandem catalytic paradigms for sustainable CO₂ conversion, highlighting the advantages over single-functional catalysts. It reviews recent progress in tandem catalysis using multifunctional catalysts in a single reactor and tandem reactors involving multiple catalysts. The benefits of tandem processes include simplified intermediate purification, reduced safety risks and environmental concerns, and the ability to produce complex and value-added products. The article also explores the application of tandem processes in thermochemical and electrochemical reactions, emphasizing the importance of catalyst compatibility, proximity, and reaction conditions. It provides guidance on selecting between single reactors with multifunctional catalysts and tandem reactors, and discusses the potential of hybrid tandem processes involving biocatalysis, photocatalysis, and plasma-assisted catalysis. The outlook section emphasizes the need for further research to understand the effects of by-products and unreacted CO₂, and to develop standardized metrics for performance evaluation. The article concludes by highlighting the potential of tandem processes to convert CO₂ into valuable products and the importance of considering energy costs and CO₂ footprint in their evaluation.This perspective discusses the potential of tandem catalytic paradigms for sustainable CO₂ conversion, highlighting the advantages over single-functional catalysts. It reviews recent progress in tandem catalysis using multifunctional catalysts in a single reactor and tandem reactors involving multiple catalysts. The benefits of tandem processes include simplified intermediate purification, reduced safety risks and environmental concerns, and the ability to produce complex and value-added products. The article also explores the application of tandem processes in thermochemical and electrochemical reactions, emphasizing the importance of catalyst compatibility, proximity, and reaction conditions. It provides guidance on selecting between single reactors with multifunctional catalysts and tandem reactors, and discusses the potential of hybrid tandem processes involving biocatalysis, photocatalysis, and plasma-assisted catalysis. The outlook section emphasizes the need for further research to understand the effects of by-products and unreacted CO₂, and to develop standardized metrics for performance evaluation. The article concludes by highlighting the potential of tandem processes to convert CO₂ into valuable products and the importance of considering energy costs and CO₂ footprint in their evaluation.