The EMBL-EBI Job Dispatcher sequence analysis tools framework provides a range of bioinformatics applications for sequence analysis, accessible via web interfaces and APIs. It integrates with EMBL-EBI resources such as UniProt, InterPro, ENA, and Ensembl Genomes. Recent improvements include a new website, enhanced visualizations, improved job management, and increased user reliance, particularly from low- and middle-income countries. The new website offers a user-friendly interface, a landing page for tool access, a 'Your Jobs' page for job history, and detailed tool descriptions. Interactive visualizations are available for MSA and SSS results, including phylogenetic trees and functional predictions. The documentation provides guidance on using the tools and APIs, along with training resources and FAQs. The framework supports a wide range of sequence analysis tools, including alignment, similarity search, and functional prediction tools. The service has a global user base, with over 109 million jobs processed in 2023. The framework is continuously updated and maintained, with a focus on improving accessibility, usability, and performance. The service is available through multiple platforms, including web interfaces, APIs, and GitHub repositories. The framework adheres to FAIR principles and is supported by EMBL-EBI.The EMBL-EBI Job Dispatcher sequence analysis tools framework provides a range of bioinformatics applications for sequence analysis, accessible via web interfaces and APIs. It integrates with EMBL-EBI resources such as UniProt, InterPro, ENA, and Ensembl Genomes. Recent improvements include a new website, enhanced visualizations, improved job management, and increased user reliance, particularly from low- and middle-income countries. The new website offers a user-friendly interface, a landing page for tool access, a 'Your Jobs' page for job history, and detailed tool descriptions. Interactive visualizations are available for MSA and SSS results, including phylogenetic trees and functional predictions. The documentation provides guidance on using the tools and APIs, along with training resources and FAQs. The framework supports a wide range of sequence analysis tools, including alignment, similarity search, and functional prediction tools. The service has a global user base, with over 109 million jobs processed in 2023. The framework is continuously updated and maintained, with a focus on improving accessibility, usability, and performance. The service is available through multiple platforms, including web interfaces, APIs, and GitHub repositories. The framework adheres to FAIR principles and is supported by EMBL-EBI.