The article reviews the molecular mechanisms induced by human papillomavirus (HPV), specifically high-risk HPV (HR-HPV), in the development of cervical cancer. It highlights ten mechanisms associated with at least seven of the fourteen hallmarks of cancer, as proposed by Hanahan in 2022. These mechanisms include infection by HPV, cellular tropism, genetic predisposition, viral load, viral physical state, regulation of epigenetic mechanisms, loss of function of the E2 protein, deregulated expression of E6/E7 oncogenes, regulation of host cell protein function, and acquisition of the mesenchymal phenotype. The review emphasizes the importance of understanding these mechanisms to identify clinically relevant biomarkers for improving the diagnosis and treatment of cervical cancer.The article reviews the molecular mechanisms induced by human papillomavirus (HPV), specifically high-risk HPV (HR-HPV), in the development of cervical cancer. It highlights ten mechanisms associated with at least seven of the fourteen hallmarks of cancer, as proposed by Hanahan in 2022. These mechanisms include infection by HPV, cellular tropism, genetic predisposition, viral load, viral physical state, regulation of epigenetic mechanisms, loss of function of the E2 protein, deregulated expression of E6/E7 oncogenes, regulation of host cell protein function, and acquisition of the mesenchymal phenotype. The review emphasizes the importance of understanding these mechanisms to identify clinically relevant biomarkers for improving the diagnosis and treatment of cervical cancer.