The Jpred 3 secondary structure prediction server, powered by the Jnet algorithm, has been updated to improve accuracy and user experience. The Jnet algorithm now predicts secondary structure with an accuracy of 81.5%, up from 76.4% in previous versions. The server can handle both single protein sequences and multiple sequence alignments, providing predictions of secondary structure and solvent accessibility. New features include batch submission of sequences, email notifications for results, and regular updates to the search databases. The user interface has been enhanced for better usability, with improved feedback, progress meters, and multiple viewing options for results. The server also includes a new semi-automatic pipeline for creating training data, ensuring that Jnet remains up-to-date with the latest sequence information. These improvements make Jpred 3 a more reliable and user-friendly tool for predicting protein secondary structure.The Jpred 3 secondary structure prediction server, powered by the Jnet algorithm, has been updated to improve accuracy and user experience. The Jnet algorithm now predicts secondary structure with an accuracy of 81.5%, up from 76.4% in previous versions. The server can handle both single protein sequences and multiple sequence alignments, providing predictions of secondary structure and solvent accessibility. New features include batch submission of sequences, email notifications for results, and regular updates to the search databases. The user interface has been enhanced for better usability, with improved feedback, progress meters, and multiple viewing options for results. The server also includes a new semi-automatic pipeline for creating training data, ensuring that Jnet remains up-to-date with the latest sequence information. These improvements make Jpred 3 a more reliable and user-friendly tool for predicting protein secondary structure.