The PRISMA 2020 statement is an updated guideline for reporting systematic reviews, replacing the 2009 version. It reflects advances in methods for identifying, selecting, appraising, and synthesizing studies. The new guideline includes a 27-item checklist, an expanded checklist with detailed reporting recommendations, an abstract checklist, and revised flow diagrams. The PRISMA 2020 statement aims to improve the transparency, completeness, and accuracy of systematic reviews, benefiting authors, editors, peer reviewers, and various stakeholders. It covers systematic reviews of health interventions, mixed-methods reviews, and reviews with different objectives. The guideline is not intended to guide review conduct or assess methodological quality but to enhance reporting. The development process involved literature reviews, surveys, and meetings. The PRISMA 2020 statement is expected to facilitate evidence-based decision-making and improve the quality of systematic reviews.The PRISMA 2020 statement is an updated guideline for reporting systematic reviews, replacing the 2009 version. It reflects advances in methods for identifying, selecting, appraising, and synthesizing studies. The new guideline includes a 27-item checklist, an expanded checklist with detailed reporting recommendations, an abstract checklist, and revised flow diagrams. The PRISMA 2020 statement aims to improve the transparency, completeness, and accuracy of systematic reviews, benefiting authors, editors, peer reviewers, and various stakeholders. It covers systematic reviews of health interventions, mixed-methods reviews, and reviews with different objectives. The guideline is not intended to guide review conduct or assess methodological quality but to enhance reporting. The development process involved literature reviews, surveys, and meetings. The PRISMA 2020 statement is expected to facilitate evidence-based decision-making and improve the quality of systematic reviews.