ChatGPT, an AI-driven large language model, has shown significant potential in the medical field, offering applications in clinical practice, healthcare, medical education, and research. This review explores its benefits, limitations, and future directions, emphasizing the need for further research to enhance its performance and ensure safe, ethical use. While ChatGPT can assist in tasks such as clinical decision support, medical documentation, and patient communication, it is not a substitute for professional medical judgment. Its responses may lack accuracy, contain biases, or be based on incomplete data, necessitating verification by medical professionals. Challenges include ethical concerns, data privacy, and the risk of misinformation. ChatGPT can aid in drug discovery, medical research, and personalized medicine, but its integration into clinical settings requires careful evaluation to ensure reliability and safety. Future research should focus on improving the model's accuracy, addressing ethical and privacy issues, and developing guidelines for its responsible use. While ChatGPT offers valuable tools for healthcare professionals, it should be used as an auxiliary resource rather than a replacement for human expertise. The review highlights the importance of balancing technological advancements with ethical considerations to ensure the safe and effective application of AI in medicine.ChatGPT, an AI-driven large language model, has shown significant potential in the medical field, offering applications in clinical practice, healthcare, medical education, and research. This review explores its benefits, limitations, and future directions, emphasizing the need for further research to enhance its performance and ensure safe, ethical use. While ChatGPT can assist in tasks such as clinical decision support, medical documentation, and patient communication, it is not a substitute for professional medical judgment. Its responses may lack accuracy, contain biases, or be based on incomplete data, necessitating verification by medical professionals. Challenges include ethical concerns, data privacy, and the risk of misinformation. ChatGPT can aid in drug discovery, medical research, and personalized medicine, but its integration into clinical settings requires careful evaluation to ensure reliability and safety. Future research should focus on improving the model's accuracy, addressing ethical and privacy issues, and developing guidelines for its responsible use. While ChatGPT offers valuable tools for healthcare professionals, it should be used as an auxiliary resource rather than a replacement for human expertise. The review highlights the importance of balancing technological advancements with ethical considerations to ensure the safe and effective application of AI in medicine.