Polyphenols, found in plants, have significant potential in treating various skin disorders due to their antioxidant, anti-inflammatory, antimicrobial, and anti-allergic properties. They can alleviate symptoms and prevent the development of skin conditions such as psoriasis, vitiligo, dermatitis, and skin cancer. Polyphenols counteract oxidative stress, which damages skin cells, DNA, and proteins, and can delay the progression of skin disorders. They also help in skin regeneration and have been shown to reduce inflammation and inhibit the growth of harmful bacteria. Polyphenols like quercetin, resveratrol, and curcumin have been studied for their ability to protect against UV radiation, reduce skin aging, and prevent melanoma. They can also inhibit the production of melanin, which is beneficial in treating hyperpigmentation. Additionally, polyphenols have been used in anti-aging cosmetics to improve skin elasticity, moisture, and texture. Despite their potential, more clinical research is needed to fully understand their therapeutic applications and to develop effective formulations for skin health.Polyphenols, found in plants, have significant potential in treating various skin disorders due to their antioxidant, anti-inflammatory, antimicrobial, and anti-allergic properties. They can alleviate symptoms and prevent the development of skin conditions such as psoriasis, vitiligo, dermatitis, and skin cancer. Polyphenols counteract oxidative stress, which damages skin cells, DNA, and proteins, and can delay the progression of skin disorders. They also help in skin regeneration and have been shown to reduce inflammation and inhibit the growth of harmful bacteria. Polyphenols like quercetin, resveratrol, and curcumin have been studied for their ability to protect against UV radiation, reduce skin aging, and prevent melanoma. They can also inhibit the production of melanin, which is beneficial in treating hyperpigmentation. Additionally, polyphenols have been used in anti-aging cosmetics to improve skin elasticity, moisture, and texture. Despite their potential, more clinical research is needed to fully understand their therapeutic applications and to develop effective formulations for skin health.