The article discusses the concept of entrepreneurial ecosystems, emphasizing their relational organization and the interdependencies among various attributes that support entrepreneurship. It argues that entrepreneurial ecosystems are not just defined by high rates of entrepreneurship but by the interactions between cultural, social, and material attributes that create a supportive environment for new ventures. The paper presents a framework identifying ten key attributes, including cultural attitudes, social networks, investment capital, and supportive policies, which together shape the ecosystem. Through case studies of Waterloo, Ontario, and Calgary, Alberta, the article illustrates how different configurations of these attributes can lead to successful entrepreneurial environments. In Calgary, the ecosystem is driven by the oil and gas industry, creating opportunities and attracting talent, while Waterloo's ecosystem is rooted in a strong entrepreneurial culture with robust networks and support systems. The study highlights the importance of understanding the relational dynamics within ecosystems to foster sustainable entrepreneurship and emphasizes that successful ecosystems are not uniform but vary based on local contexts and configurations. The findings suggest that effective policies and programs must consider these interdependencies to support entrepreneurial growth.The article discusses the concept of entrepreneurial ecosystems, emphasizing their relational organization and the interdependencies among various attributes that support entrepreneurship. It argues that entrepreneurial ecosystems are not just defined by high rates of entrepreneurship but by the interactions between cultural, social, and material attributes that create a supportive environment for new ventures. The paper presents a framework identifying ten key attributes, including cultural attitudes, social networks, investment capital, and supportive policies, which together shape the ecosystem. Through case studies of Waterloo, Ontario, and Calgary, Alberta, the article illustrates how different configurations of these attributes can lead to successful entrepreneurial environments. In Calgary, the ecosystem is driven by the oil and gas industry, creating opportunities and attracting talent, while Waterloo's ecosystem is rooted in a strong entrepreneurial culture with robust networks and support systems. The study highlights the importance of understanding the relational dynamics within ecosystems to foster sustainable entrepreneurship and emphasizes that successful ecosystems are not uniform but vary based on local contexts and configurations. The findings suggest that effective policies and programs must consider these interdependencies to support entrepreneurial growth.