The article reviews the progress in reproducing the Standard Model of Particle Physics (SM) from string theory compactifications. It highlights the unique proposal of string theory to incorporate both gauge and gravitational interactions, leading to a four-dimensional theory that unifies quantum mechanics and gravity through compactification of extra dimensions. The review covers the state-of-the-art in realizing the SM gauge group, chiral spectrum, and Yukawa couplings, as well as the mechanisms for generating hierarchies and addressing the hierarchy problem. It discusses novel scenarios and mechanisms provided by string theory, such as F-theory GUTs and the role of non-perturbative effects like instantons. The article also explores the connection between the SM and Quantum Gravity, emphasizing recent developments that may change our understanding of naturalness in field theory. Finally, it reflects on the lessons learned from this fascinating quest, including the challenges and opportunities in string phenomenology.The article reviews the progress in reproducing the Standard Model of Particle Physics (SM) from string theory compactifications. It highlights the unique proposal of string theory to incorporate both gauge and gravitational interactions, leading to a four-dimensional theory that unifies quantum mechanics and gravity through compactification of extra dimensions. The review covers the state-of-the-art in realizing the SM gauge group, chiral spectrum, and Yukawa couplings, as well as the mechanisms for generating hierarchies and addressing the hierarchy problem. It discusses novel scenarios and mechanisms provided by string theory, such as F-theory GUTs and the role of non-perturbative effects like instantons. The article also explores the connection between the SM and Quantum Gravity, emphasizing recent developments that may change our understanding of naturalness in field theory. Finally, it reflects on the lessons learned from this fascinating quest, including the challenges and opportunities in string phenomenology.