The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

27 November 1997 | Hans-Peter Klenk, Rebecca A. Clayton, Jean-Francois Tomb, Owen White, Karen E. Nelson, Karen A. Ketchum, Robert J. Dodson, Michelle Gwinn, Erin K. Hickey, Jeremy D. Peterson, Delwood L. Richardson, Anthony R. Kerlavage, David E. Graham, Nikos C. Kyprides, Robert D. Fleischmann, John Quackenbush, Norman H. Lee, Granger G. Sutton, Steven Gill, Ewen F. Kirkness, Brian A. Dougherty, Keith McKenney, Mark D. Adams, Brendan Loftus, Scott Peterson, Claudia I. Reich, Leslie K. McNeil, Jonathan H. Badger, Anna Glodek, Lixin Zhou, Ross Overbeek, Jeannine D. Gocayne, Janice F. Weidman, Lisa McDonald, Teresa Utterback, Matthew D. Cotton, Tracy Spriggs, Patricia Artiach, Brian P. Kaine, Sean M. Sykes, Paul W. Sadow, Kurt P. D'Andrea, Cheryl Bowman, Claire Fujii, Stacey A. Garland, Tanya M. Mason, Gary J. Olsen, Claire M. Fraser, Hamilton O. Smith, Carl R. Woese & J. Craig Venter
The provided text includes a list of scientific references and a detailed article on the complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon *Archaeoglobus fulgidus*. The references cover various studies on protein-DNA interactions, structural biology, and genome sequencing techniques. The main article describes the genome of *A. fulgidus*, which is the first sulphur-metabolizing organism to have its genome sequenced. The genome consists of a single circular chromosome of 2,178,400 base pairs with a G+C content of 48.5%. It contains 2,436 open reading frames (ORFs), with a significant portion of the genome encoding functionally uncharacterized yet conserved proteins. The genome shows extensive correlation with the archaeon *Methanococcus jannaschii* in terms of information processing systems and biosynthetic pathways for essential components. However, *A. fulgidus* differs from *M. jannaschii* in its environmental sensing, regulatory, and transport functions, as well as in its energy acquisition mechanisms. The article also discusses the metabolic pathways of *A. fulgidus*, including sulphate reduction, carbon metabolism, and energy production. It highlights the organism's ability to use various carbon and energy sources, including fatty acids, amino acids, and organic acids. The genome also contains genes for multiple catabolic pathways, including those for CoA-SH-dependent ferredoxin oxidoreductases and tungsten-containing aldehyde ferredoxin oxidoreductases. The article further describes the transport systems of *A. fulgidus*, including the import of carbon-containing compounds and the regulation of ion homeostasis. It also discusses the sensory functions and regulation of gene expression, as well as the replication, repair, and cell division mechanisms of the organism. The article concludes with a discussion of the evolutionary significance of gene duplication in *A. fulgidus* and the comparison of its genome with that of *M. jannaschii*. The text also includes a list of references to various studies on protein-DNA interactions, structural biology, and genome sequencing techniques.The provided text includes a list of scientific references and a detailed article on the complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon *Archaeoglobus fulgidus*. The references cover various studies on protein-DNA interactions, structural biology, and genome sequencing techniques. The main article describes the genome of *A. fulgidus*, which is the first sulphur-metabolizing organism to have its genome sequenced. The genome consists of a single circular chromosome of 2,178,400 base pairs with a G+C content of 48.5%. It contains 2,436 open reading frames (ORFs), with a significant portion of the genome encoding functionally uncharacterized yet conserved proteins. The genome shows extensive correlation with the archaeon *Methanococcus jannaschii* in terms of information processing systems and biosynthetic pathways for essential components. However, *A. fulgidus* differs from *M. jannaschii* in its environmental sensing, regulatory, and transport functions, as well as in its energy acquisition mechanisms. The article also discusses the metabolic pathways of *A. fulgidus*, including sulphate reduction, carbon metabolism, and energy production. It highlights the organism's ability to use various carbon and energy sources, including fatty acids, amino acids, and organic acids. The genome also contains genes for multiple catabolic pathways, including those for CoA-SH-dependent ferredoxin oxidoreductases and tungsten-containing aldehyde ferredoxin oxidoreductases. The article further describes the transport systems of *A. fulgidus*, including the import of carbon-containing compounds and the regulation of ion homeostasis. It also discusses the sensory functions and regulation of gene expression, as well as the replication, repair, and cell division mechanisms of the organism. The article concludes with a discussion of the evolutionary significance of gene duplication in *A. fulgidus* and the comparison of its genome with that of *M. jannaschii*. The text also includes a list of references to various studies on protein-DNA interactions, structural biology, and genome sequencing techniques.
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Understanding The complete genome sequence of the hyperthermophilic%2C sulphate-reducing archaeon Archaeoglobus fulgidus