Three neurons stretch across both brain hemispheres, with one wrapping around the brain like a "crown of thorns," according to Koch. He notes that such extensive neuron extension across brain regions is rare. These claustrum neurons connect to most or all of the brain's outer regions that process sensory information and drive behavior. Koch suggests this may indicate the claustrum coordinates brain inputs and outputs for consciousness. The human claustrum is highly connected, but individual neuron paths are not visible in brain scans. The claustrum is a good region to test new techniques due to its extensive study in mice and limited cell types. Yuste acknowledges the method's value for identifying brain cell types but notes it doesn't definitively prove the claustrum's role in consciousness. Comparing 3D neuron reconstructions with gene expression data could reveal cell types and functions. It is unclear if gene-expression patterns correlate with neuron shape, and imaging techniques like those from the Allen Institute may help clarify this. Koch plans to continue mapping claustrum neurons, though the technique is too costly for large-scale reconstruction. He wants to know if all neurons extend throughout the brain or if each is unique. The World Health Organization has released a list of drug-resistant bacteria posing the greatest threat, aiming to direct resources toward developing new antibiotics. The list includes carbapenem-resistant Acinetobacter baumannii and other multidrug-resistant pathogens. Antibiotic resistance kills 700,000 people annually, with projections of 10 million by 2050. However, the antibiotic development pipeline is limited, with only 40 new antibiotics in clinical development compared to hundreds of cancer drugs. Developing antibiotics is challenging, and many companies view them as a losing proposition. The WHO list, while useful, does not guarantee that drug developers will prioritize the top pathogens. The list was created by considering factors like deadliness, resistance, and spread, excluding pathogens that can be addressed by other means.Three neurons stretch across both brain hemispheres, with one wrapping around the brain like a "crown of thorns," according to Koch. He notes that such extensive neuron extension across brain regions is rare. These claustrum neurons connect to most or all of the brain's outer regions that process sensory information and drive behavior. Koch suggests this may indicate the claustrum coordinates brain inputs and outputs for consciousness. The human claustrum is highly connected, but individual neuron paths are not visible in brain scans. The claustrum is a good region to test new techniques due to its extensive study in mice and limited cell types. Yuste acknowledges the method's value for identifying brain cell types but notes it doesn't definitively prove the claustrum's role in consciousness. Comparing 3D neuron reconstructions with gene expression data could reveal cell types and functions. It is unclear if gene-expression patterns correlate with neuron shape, and imaging techniques like those from the Allen Institute may help clarify this. Koch plans to continue mapping claustrum neurons, though the technique is too costly for large-scale reconstruction. He wants to know if all neurons extend throughout the brain or if each is unique. The World Health Organization has released a list of drug-resistant bacteria posing the greatest threat, aiming to direct resources toward developing new antibiotics. The list includes carbapenem-resistant Acinetobacter baumannii and other multidrug-resistant pathogens. Antibiotic resistance kills 700,000 people annually, with projections of 10 million by 2050. However, the antibiotic development pipeline is limited, with only 40 new antibiotics in clinical development compared to hundreds of cancer drugs. Developing antibiotics is challenging, and many companies view them as a losing proposition. The WHO list, while useful, does not guarantee that drug developers will prioritize the top pathogens. The list was created by considering factors like deadliness, resistance, and spread, excluding pathogens that can be addressed by other means.