This systematic review and meta-analysis examines the impact of the COVID-19 pandemic on nurses' job satisfaction. The study aimed to identify factors influencing job satisfaction, explore the consequences of job dissatisfaction, and investigate countermeasures to mitigate dissatisfaction. Using the Joanna Briggs Institute methodology, the review searched multiple databases from January 2020 to February 2023, identifying 23 studies from 20 countries. The pooled prevalence of job satisfaction was 69.6%, with significant factors affecting satisfaction including personal and demographic characteristics, work environment, and psychological and emotional factors. High job satisfaction was linked to improved psychological well-being, quality of life, and patient care, while dissatisfaction was associated with turnover, mental health issues, and reduced job performance. The review also identified interventions such as motivational messages and organizational support that positively influenced job satisfaction. The findings highlight the importance of addressing job satisfaction to enhance nurses' well-being and healthcare delivery during and after the pandemic.This systematic review and meta-analysis examines the impact of the COVID-19 pandemic on nurses' job satisfaction. The study aimed to identify factors influencing job satisfaction, explore the consequences of job dissatisfaction, and investigate countermeasures to mitigate dissatisfaction. Using the Joanna Briggs Institute methodology, the review searched multiple databases from January 2020 to February 2023, identifying 23 studies from 20 countries. The pooled prevalence of job satisfaction was 69.6%, with significant factors affecting satisfaction including personal and demographic characteristics, work environment, and psychological and emotional factors. High job satisfaction was linked to improved psychological well-being, quality of life, and patient care, while dissatisfaction was associated with turnover, mental health issues, and reduced job performance. The review also identified interventions such as motivational messages and organizational support that positively influenced job satisfaction. The findings highlight the importance of addressing job satisfaction to enhance nurses' well-being and healthcare delivery during and after the pandemic.