The study estimates the global prevalence of open-angle glaucoma (OAG) and angle closure glaucoma (ACG) in 2010 and 2020. In 2010, there were approximately 60.5 million people with glaucoma, increasing to 79.6 million by 2020. Of these, 74% had OAG, and 26% had ACG. Women accounted for 55% of OAG cases, 70% of ACG cases, and 59% of all glaucoma cases. Asians represented 47% of all glaucoma cases and 87% of ACG cases. Bilateral blindness was present in 4.5 million OAG cases and 3.9 million ACG cases in 2010, rising to 5.9 million and 5.3 million by 2020, respectively. Glaucoma is the second leading cause of blindness worldwide, disproportionately affecting women and Asians. The study used prevalence models based on age, sex, and ethnicity, combined with UN population projections to estimate the number of people with glaucoma. The results highlight the increasing burden of glaucoma, with India becoming the second largest affected region by 2020. The study emphasizes the need for improved diagnostic and therapeutic approaches to glaucoma to address the growing global burden.The study estimates the global prevalence of open-angle glaucoma (OAG) and angle closure glaucoma (ACG) in 2010 and 2020. In 2010, there were approximately 60.5 million people with glaucoma, increasing to 79.6 million by 2020. Of these, 74% had OAG, and 26% had ACG. Women accounted for 55% of OAG cases, 70% of ACG cases, and 59% of all glaucoma cases. Asians represented 47% of all glaucoma cases and 87% of ACG cases. Bilateral blindness was present in 4.5 million OAG cases and 3.9 million ACG cases in 2010, rising to 5.9 million and 5.3 million by 2020, respectively. Glaucoma is the second leading cause of blindness worldwide, disproportionately affecting women and Asians. The study used prevalence models based on age, sex, and ethnicity, combined with UN population projections to estimate the number of people with glaucoma. The results highlight the increasing burden of glaucoma, with India becoming the second largest affected region by 2020. The study emphasizes the need for improved diagnostic and therapeutic approaches to glaucoma to address the growing global burden.