The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension

The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension

02 February 2024 | Rosamaria Caminiti, Cristina Carresi, Rocco Mollace, Roberta Macri, Federica Scarano, Francesca Oppedisano, Jessica Maiuolo, Maria Serra, Stefano Ruga, Saverio Nucera, Annamaria Tavernese, Micaela Gliozzi, Vincenzo Musolino, Ernesto Palma, Carolina Muscoli, Speranza Rubattu, Maurizio Volterrani, Massimo Federici, Massimo Volpe
Natural antioxidants may help counteract arterial hypertension by improving endothelial function. Arterial hypertension is a major cause of cardiovascular disease, and endothelial dysfunction plays a key role in its development. Endothelial cells produce vasoactive substances, including nitric oxide (NO), which helps regulate blood pressure. However, hypertension is associated with increased oxidative stress, which impairs endothelial function and contributes to vascular damage. Natural antioxidants, such as those found in plant extracts, may help reduce oxidative stress and improve endothelial function, potentially preventing or managing hypertension. Studies suggest that antioxidants can enhance endothelial cell viability and reduce oxidative damage, which may help maintain normal blood pressure. Additionally, antioxidants may reduce inflammation and improve vascular health, which are important factors in hypertension. The role of natural antioxidants in hypertension treatment is an area of active research, with potential applications in both preventing and managing the condition. The mechanisms by which antioxidants exert their effects include reducing oxidative stress, improving NO availability, and modulating inflammatory responses. These findings highlight the potential of natural antioxidants as complementary therapies for hypertension management.Natural antioxidants may help counteract arterial hypertension by improving endothelial function. Arterial hypertension is a major cause of cardiovascular disease, and endothelial dysfunction plays a key role in its development. Endothelial cells produce vasoactive substances, including nitric oxide (NO), which helps regulate blood pressure. However, hypertension is associated with increased oxidative stress, which impairs endothelial function and contributes to vascular damage. Natural antioxidants, such as those found in plant extracts, may help reduce oxidative stress and improve endothelial function, potentially preventing or managing hypertension. Studies suggest that antioxidants can enhance endothelial cell viability and reduce oxidative damage, which may help maintain normal blood pressure. Additionally, antioxidants may reduce inflammation and improve vascular health, which are important factors in hypertension. The role of natural antioxidants in hypertension treatment is an area of active research, with potential applications in both preventing and managing the condition. The mechanisms by which antioxidants exert their effects include reducing oxidative stress, improving NO availability, and modulating inflammatory responses. These findings highlight the potential of natural antioxidants as complementary therapies for hypertension management.
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Understanding The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension