Thyroid disorders, including both hypothyroidism and hyperthyroidism, can significantly impact gastrointestinal (GI) motility. Hypothyroidism, characterized by reduced thyroid hormone levels, can lead to impaired GI motility, affecting the pharynx, esophagus, and stomach. Symptoms such as delayed gastric emptying, constipation, and abdominal pain are common. In contrast, hyperthyroidism, marked by elevated thyroid hormone levels, can cause rapid or normal gastric emptying, increased acid secretion, and diarrhea. The exact mechanisms linking thyroid hormones to GI motility are not fully understood, but it is known that muscle cell receptors can be directly affected by thyroxines. Treatment for thyroid disorders, such as hormone replacement therapy, can improve GI symptoms. Additionally, improving GI health through measures like probiotics or addressing food sensitivities can enhance the absorption of thyroid medication, further benefiting patients with thyroid-related GI issues. Overall, the relationship between thyroid disorders and GI dysmotility is complex and multifaceted, highlighting the importance of comprehensive evaluation and management.Thyroid disorders, including both hypothyroidism and hyperthyroidism, can significantly impact gastrointestinal (GI) motility. Hypothyroidism, characterized by reduced thyroid hormone levels, can lead to impaired GI motility, affecting the pharynx, esophagus, and stomach. Symptoms such as delayed gastric emptying, constipation, and abdominal pain are common. In contrast, hyperthyroidism, marked by elevated thyroid hormone levels, can cause rapid or normal gastric emptying, increased acid secretion, and diarrhea. The exact mechanisms linking thyroid hormones to GI motility are not fully understood, but it is known that muscle cell receptors can be directly affected by thyroxines. Treatment for thyroid disorders, such as hormone replacement therapy, can improve GI symptoms. Additionally, improving GI health through measures like probiotics or addressing food sensitivities can enhance the absorption of thyroid medication, further benefiting patients with thyroid-related GI issues. Overall, the relationship between thyroid disorders and GI dysmotility is complex and multifaceted, highlighting the importance of comprehensive evaluation and management.