The article discusses the investigation of iron deficiency anaemia, emphasizing the importance of gastrointestinal endoscopy in diagnosing the condition. It argues that gastrointestinal endoscopy should always be used to examine both the upper and lower gastrointestinal tract, as it allows for the detection of small mucosal lesions, estimation of blood loss, and biopsy sampling. The authors also stress the importance of screening for coeliac disease through small bowel biopsy, as it is a common cause of iron deficiency anaemia. They also note that faecal occult blood testing is of limited value in the initial investigation of iron deficiency anaemia, as many gastrointestinal cancers and colorectal polyps bleed intermittently. The article also highlights the importance of considering other potential causes of iron deficiency anaemia, such as haemorrhoids, colonic diverticular disease, and hiatus hernia. The authors also mention that the use of barium studies is not as effective as endoscopy in diagnosing iron deficiency anaemia. The article concludes that the investigation of iron deficiency anaemia should be limited to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema when there is no obvious source of blood loss. The authors also acknowledge that the article may have been superficial and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of ironThe article discusses the investigation of iron deficiency anaemia, emphasizing the importance of gastrointestinal endoscopy in diagnosing the condition. It argues that gastrointestinal endoscopy should always be used to examine both the upper and lower gastrointestinal tract, as it allows for the detection of small mucosal lesions, estimation of blood loss, and biopsy sampling. The authors also stress the importance of screening for coeliac disease through small bowel biopsy, as it is a common cause of iron deficiency anaemia. They also note that faecal occult blood testing is of limited value in the initial investigation of iron deficiency anaemia, as many gastrointestinal cancers and colorectal polyps bleed intermittently. The article also highlights the importance of considering other potential causes of iron deficiency anaemia, such as haemorrhoids, colonic diverticular disease, and hiatus hernia. The authors also mention that the use of barium studies is not as effective as endoscopy in diagnosing iron deficiency anaemia. The article concludes that the investigation of iron deficiency anaemia should be limited to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema when there is no obvious source of blood loss. The authors also acknowledge that the article may have been superficial and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron deficiency anaemia. The authors argue that their approach is more comprehensive and that the previous article was too brief. The article also mentions that the authors have shown that it is safe to limit the investigation of patients with iron deficiency of no obvious cause to upper gastrointestinal endoscopy, small bowel biopsy, and barium enema. The authors also note that the article may have been too brief and that more detailed information could have been provided. The article is a response to a previous article that suggested a more limited approach to the investigation of iron