This study investigates the photocatalytic degradation of sulfamethoxazole (SMX) in water using TiO₂/zeolite composites under UV light irradiation. Two composite materials, TZSM1450 and TZSM2600, were prepared by mechanical mixing and liquid impregnation methods, respectively. The photocatalytic performance of these composites was evaluated for SMX degradation at a concentration of 30 mg/L in water. The results showed that the TZSM1450 composite exhibited the highest degradation efficiency, achieving 100% SMX degradation within 10 minutes. The pseudo-first-order rate constant (k_d) for SMX degradation was 0.501 min⁻¹ for TZSM1450, which was 2.08 times higher than that of pure TiO₂ (k_d = 0.241 min⁻¹). Additionally, the TZSM1450 composite showed excellent mineralization ability, with 67% of SMX mineralized within 120 minutes. The presence of Cl⁻ and CO₃²⁻ anions inhibited SMX degradation, while NO₃⁻ had minimal effect. The electrical energy per order (EE/O) for SMX degradation was estimated as 68.53 kWh m⁻³ order⁻¹ for the TZSM1450 composite, making it a promising catalyst for effective SMX elimination from water.This study investigates the photocatalytic degradation of sulfamethoxazole (SMX) in water using TiO₂/zeolite composites under UV light irradiation. Two composite materials, TZSM1450 and TZSM2600, were prepared by mechanical mixing and liquid impregnation methods, respectively. The photocatalytic performance of these composites was evaluated for SMX degradation at a concentration of 30 mg/L in water. The results showed that the TZSM1450 composite exhibited the highest degradation efficiency, achieving 100% SMX degradation within 10 minutes. The pseudo-first-order rate constant (k_d) for SMX degradation was 0.501 min⁻¹ for TZSM1450, which was 2.08 times higher than that of pure TiO₂ (k_d = 0.241 min⁻¹). Additionally, the TZSM1450 composite showed excellent mineralization ability, with 67% of SMX mineralized within 120 minutes. The presence of Cl⁻ and CO₃²⁻ anions inhibited SMX degradation, while NO₃⁻ had minimal effect. The electrical energy per order (EE/O) for SMX degradation was estimated as 68.53 kWh m⁻³ order⁻¹ for the TZSM1450 composite, making it a promising catalyst for effective SMX elimination from water.