The chapter emphasizes the importance of recognizing and supporting Indigenous science in addressing the challenges of a rapidly changing environment. Indigenous knowledge, often marginalized by Western science, is gaining recognition and respect, as evidenced by the White House's call for its integration into research, policy, and land management. The establishment of the Center for Braiding Indigenous Knowledges and Science (CBIKS) by the US National Science Foundation is a significant step, aiming to integrate Indigenous and Western sciences through ethical and effective collaboration. This initiative, led by Indigenous scholars, focuses on complex issues like climate disruption, food insecurity, and cultural survival. Similar efforts in other countries, such as Australia, Canada, and New Zealand, are also underway. The chapter stresses the need for institutions to support Indigenous communities rather than extract their knowledge for external gain, and to address institutional barriers that limit Indigenous participation and visibility. It calls for policies that value pluralism while protecting the sovereignty and rights of Indigenous peoples, fostering a symbiotic relationship between Western and Indigenous knowledges for mutual benefit.The chapter emphasizes the importance of recognizing and supporting Indigenous science in addressing the challenges of a rapidly changing environment. Indigenous knowledge, often marginalized by Western science, is gaining recognition and respect, as evidenced by the White House's call for its integration into research, policy, and land management. The establishment of the Center for Braiding Indigenous Knowledges and Science (CBIKS) by the US National Science Foundation is a significant step, aiming to integrate Indigenous and Western sciences through ethical and effective collaboration. This initiative, led by Indigenous scholars, focuses on complex issues like climate disruption, food insecurity, and cultural survival. Similar efforts in other countries, such as Australia, Canada, and New Zealand, are also underway. The chapter stresses the need for institutions to support Indigenous communities rather than extract their knowledge for external gain, and to address institutional barriers that limit Indigenous participation and visibility. It calls for policies that value pluralism while protecting the sovereignty and rights of Indigenous peoples, fostering a symbiotic relationship between Western and Indigenous knowledges for mutual benefit.