This review evaluates the use of microfluidic systems for the efficient synthesis of organic molecules. Microfluidic systems offer significant advantages over traditional large-scale synthetic methods, providing higher control over growth, nucleation, and reaction conditions. These systems are crucial for the rapid, affordable, and efficient manufacture of complex organic and organometallic compounds. The review highlights the benefits of microfluidic synthesis, including reduced sample volumes, improved yield and purity, space savings, lower costs, and reduced environmental impact. It also discusses the application of microfluidic devices in various fields such as pharmaceuticals, photocatalysis, biochemistry, and fine chemical production. Specific examples include the synthesis of metal complexes, protein complexes, and organic ligands, as well as the development of multifunctional nanoparticles for drug delivery and the production of azo compounds. The review emphasizes the potential of microfluidic systems to revolutionize industrial applications by improving efficiency, precision, and safety.This review evaluates the use of microfluidic systems for the efficient synthesis of organic molecules. Microfluidic systems offer significant advantages over traditional large-scale synthetic methods, providing higher control over growth, nucleation, and reaction conditions. These systems are crucial for the rapid, affordable, and efficient manufacture of complex organic and organometallic compounds. The review highlights the benefits of microfluidic synthesis, including reduced sample volumes, improved yield and purity, space savings, lower costs, and reduced environmental impact. It also discusses the application of microfluidic devices in various fields such as pharmaceuticals, photocatalysis, biochemistry, and fine chemical production. Specific examples include the synthesis of metal complexes, protein complexes, and organic ligands, as well as the development of multifunctional nanoparticles for drug delivery and the production of azo compounds. The review emphasizes the potential of microfluidic systems to revolutionize industrial applications by improving efficiency, precision, and safety.