The introduction of OpenAI's ChatGPT-4omni (GPT-4o) represents a significant advancement in virtual healthcare and telemedicine. GPT-4o excels in processing audio, visual, and textual data in real-time, enhancing natural language understanding across English and non-English contexts. The new "Temporary Chat" feature improves privacy and data confidentiality during interactions, potentially increasing integration with healthcare systems. These innovations promise to enhance communication clarity, facilitate the integration of medical images, and increase data privacy in online consultations. The editorial explores the future implications of these advancements for telemedicine, emphasizing the need for further research on reliability and the integration of advanced language models with human expertise. Key benefits include improved patient communication, enhanced efficiency, and better accessibility to high-quality healthcare services, especially in underserved and remote areas. However, the limitations of the technology, such as the potential for errors and the need for human oversight, are also highlighted. The authors propose a three-pillar online consultation integration model involving patients, healthcare professionals, and GPT-4o, while advocating for proper use to ensure patient care is not compromised.The introduction of OpenAI's ChatGPT-4omni (GPT-4o) represents a significant advancement in virtual healthcare and telemedicine. GPT-4o excels in processing audio, visual, and textual data in real-time, enhancing natural language understanding across English and non-English contexts. The new "Temporary Chat" feature improves privacy and data confidentiality during interactions, potentially increasing integration with healthcare systems. These innovations promise to enhance communication clarity, facilitate the integration of medical images, and increase data privacy in online consultations. The editorial explores the future implications of these advancements for telemedicine, emphasizing the need for further research on reliability and the integration of advanced language models with human expertise. Key benefits include improved patient communication, enhanced efficiency, and better accessibility to high-quality healthcare services, especially in underserved and remote areas. However, the limitations of the technology, such as the potential for errors and the need for human oversight, are also highlighted. The authors propose a three-pillar online consultation integration model involving patients, healthcare professionals, and GPT-4o, while advocating for proper use to ensure patient care is not compromised.