A randomized controlled trial compared complicated grief treatment (CGT) with interpersonal psychotherapy (IPT) for treating complicated grief. The study involved 95 participants, with 46 receiving IPT and 49 receiving CGT. Both treatments were delivered over 16 sessions over an average of 19 weeks. CGT showed greater response rates (51%) compared to IPT (28%) and faster time to response. The number needed to treat was 4.3. Complicated grief is a debilitating condition associated with significant distress and impairment, often requiring specific treatment. It differs from depression and PTSD, with key features including disbelief in the death, anger, recurrent painful emotions, and preoccupation with the deceased. The Inventory of Complicated Grief (ICG) is used to identify complicated grief more than 6 months after a loved one's death. CGT, based on cognitive-behavioral techniques and modified IPT, addressed trauma-like symptoms through retelling the death story and confronting avoided situations. The study found that CGT was more effective than IPT in reducing complicated grief symptoms. The results suggest that CGT is a more effective treatment for complicated grief than IPT, with higher response rates and faster time to response. The study also highlighted the need for further research to confirm these findings and explore potential moderators of treatment response. The study had limitations, including a high dropout rate and the inclusion of participants with co-occurring mental health conditions. Overall, the findings support the development of targeted treatments for complicated grief.A randomized controlled trial compared complicated grief treatment (CGT) with interpersonal psychotherapy (IPT) for treating complicated grief. The study involved 95 participants, with 46 receiving IPT and 49 receiving CGT. Both treatments were delivered over 16 sessions over an average of 19 weeks. CGT showed greater response rates (51%) compared to IPT (28%) and faster time to response. The number needed to treat was 4.3. Complicated grief is a debilitating condition associated with significant distress and impairment, often requiring specific treatment. It differs from depression and PTSD, with key features including disbelief in the death, anger, recurrent painful emotions, and preoccupation with the deceased. The Inventory of Complicated Grief (ICG) is used to identify complicated grief more than 6 months after a loved one's death. CGT, based on cognitive-behavioral techniques and modified IPT, addressed trauma-like symptoms through retelling the death story and confronting avoided situations. The study found that CGT was more effective than IPT in reducing complicated grief symptoms. The results suggest that CGT is a more effective treatment for complicated grief than IPT, with higher response rates and faster time to response. The study also highlighted the need for further research to confirm these findings and explore potential moderators of treatment response. The study had limitations, including a high dropout rate and the inclusion of participants with co-occurring mental health conditions. Overall, the findings support the development of targeted treatments for complicated grief.