The article examines trends in public confidence in science and the factors influencing these perceptions. The National Academies' Strategic Council for Research Excellence, Integrity, and Trust (the Strategic Council) analyzed data from multiple survey organizations to understand recent changes in public confidence. The findings indicate that while public confidence in science is generally high compared to other civic, cultural, and governmental institutions, it has declined over the past five years. However, this decline is similar or less pronounced than the declines in confidence in other institutions. The study also reveals that while many U.S. adults have high levels of confidence in scientists' competence, trustworthiness, and honesty, they question whether scientists align their values with their findings and can overcome personal biases. For example, 70% of respondents believe that scientists will not publish findings that run counter to the interests of their organizations. Despite these concerns, large majorities agree on specific actions scientists should take, such as disclosing their funders (84%) and being open to changing their minds based on new evidence (92%). The article further discusses the implications of these findings for increasing public confidence in science. It emphasizes the importance of maintaining a culture of critique and correction, peer review, transparency, and accountability in scientific practices. The Strategic Council's efforts include initiatives to improve conflict of interest disclosure, enhance the retraction process, and integrate scientific integrity and research ethics into scientific practices. These actions are crucial for sustaining public confidence in scientific findings and ensuring the integrity of scientific research.The article examines trends in public confidence in science and the factors influencing these perceptions. The National Academies' Strategic Council for Research Excellence, Integrity, and Trust (the Strategic Council) analyzed data from multiple survey organizations to understand recent changes in public confidence. The findings indicate that while public confidence in science is generally high compared to other civic, cultural, and governmental institutions, it has declined over the past five years. However, this decline is similar or less pronounced than the declines in confidence in other institutions. The study also reveals that while many U.S. adults have high levels of confidence in scientists' competence, trustworthiness, and honesty, they question whether scientists align their values with their findings and can overcome personal biases. For example, 70% of respondents believe that scientists will not publish findings that run counter to the interests of their organizations. Despite these concerns, large majorities agree on specific actions scientists should take, such as disclosing their funders (84%) and being open to changing their minds based on new evidence (92%). The article further discusses the implications of these findings for increasing public confidence in science. It emphasizes the importance of maintaining a culture of critique and correction, peer review, transparency, and accountability in scientific practices. The Strategic Council's efforts include initiatives to improve conflict of interest disclosure, enhance the retraction process, and integrate scientific integrity and research ethics into scientific practices. These actions are crucial for sustaining public confidence in scientific findings and ensuring the integrity of scientific research.