Ultrasound elastography is a medical imaging technique that evaluates tissue stiffness, offering non-invasive assessment of mechanical properties for diagnostic purposes. This review discusses the principles, clinical applications, and limitations of ultrasound elastography (USE). The technique uses changes in tissue elasticity to generate qualitative and quantitative data, aiding in the diagnosis of diseases such as liver fibrosis, breast cancer, and kidney fibrosis. USE employs methods like strain imaging and shear wave imaging to assess tissue stiffness, with shear wave imaging being particularly effective for liver fibrosis detection. Techniques such as 1D-TE, 2D-SWE, and pSWE are used for different clinical applications, with 2D-SWE showing high accuracy in detecting fibrosis stages. However, technical limitations, including image artifacts, patient obesity, and motion effects, can impact the accuracy of USE. Despite these challenges, USE is a valuable tool for non-invasive diagnosis and monitoring of various diseases, offering advantages over traditional methods. The review highlights the importance of continued research to improve the reliability and application of ultrasound elastography in clinical settings.Ultrasound elastography is a medical imaging technique that evaluates tissue stiffness, offering non-invasive assessment of mechanical properties for diagnostic purposes. This review discusses the principles, clinical applications, and limitations of ultrasound elastography (USE). The technique uses changes in tissue elasticity to generate qualitative and quantitative data, aiding in the diagnosis of diseases such as liver fibrosis, breast cancer, and kidney fibrosis. USE employs methods like strain imaging and shear wave imaging to assess tissue stiffness, with shear wave imaging being particularly effective for liver fibrosis detection. Techniques such as 1D-TE, 2D-SWE, and pSWE are used for different clinical applications, with 2D-SWE showing high accuracy in detecting fibrosis stages. However, technical limitations, including image artifacts, patient obesity, and motion effects, can impact the accuracy of USE. Despite these challenges, USE is a valuable tool for non-invasive diagnosis and monitoring of various diseases, offering advantages over traditional methods. The review highlights the importance of continued research to improve the reliability and application of ultrasound elastography in clinical settings.