The article "Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications" by Hussan Munir et al. explores the nutraceutical and therapeutic potential of citrus peels. Citrus peels, rich in flavonoids and essential oils, exhibit high antioxidant and anti-inflammatory properties, making them valuable for dietary interventions. The authors highlight the global production of citrus peels, which amounts to approximately 15 million tons annually, and discuss the extraction methods, including supercritical fluid extraction, which is favored for its efficiency and environmental benefits. The article also reviews the chemical composition of citrus peels, emphasizing the presence of flavanones like hesperidin and naringin, and polymethoxylated flavones. The antioxidant and anti-inflammatory activities of citrus peels are detailed, with studies showing their effectiveness in reducing oxidative stress and inflammatory markers. Additionally, the article discusses the use of citrus peels in food products, such as baked goods, and their potential in pharmaceutical applications, including as natural preservatives and in traditional medicine. The authors conclude by emphasizing the need for increased awareness and utilization of citrus peels to promote health and well-being.The article "Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications" by Hussan Munir et al. explores the nutraceutical and therapeutic potential of citrus peels. Citrus peels, rich in flavonoids and essential oils, exhibit high antioxidant and anti-inflammatory properties, making them valuable for dietary interventions. The authors highlight the global production of citrus peels, which amounts to approximately 15 million tons annually, and discuss the extraction methods, including supercritical fluid extraction, which is favored for its efficiency and environmental benefits. The article also reviews the chemical composition of citrus peels, emphasizing the presence of flavanones like hesperidin and naringin, and polymethoxylated flavones. The antioxidant and anti-inflammatory activities of citrus peels are detailed, with studies showing their effectiveness in reducing oxidative stress and inflammatory markers. Additionally, the article discusses the use of citrus peels in food products, such as baked goods, and their potential in pharmaceutical applications, including as natural preservatives and in traditional medicine. The authors conclude by emphasizing the need for increased awareness and utilization of citrus peels to promote health and well-being.