The American College of Veterinary Internal Medicine (ACVIM) publishes consensus statements to provide up-to-date information on animal diseases. The updated consensus statement on equine herpesvirus-1 (EHV-1) addresses vaccination, treatment, diagnosis, and pathogenesis. The statement is based on systematic reviews and highlights the limitations of current evidence. Vaccination has limited effectiveness in preventing EHV-1 infection and disease, and pharmacologic treatments show minimal efficacy. Viremia is a key factor in the occurrence of abortion and EHM, but the relationship between viremia levels and disease outcomes is not fully understood. The best sampling strategy for EHV-1 detection involves testing both nasal secretions and blood, with nasal secretions being more effective in certain cases. The consensus statement also updates the 2009 statement, emphasizing the need for further research. The statement recommends vaccination as part of a biosecurity program, despite limited evidence of effectiveness. It also highlights the importance of early diagnosis, prevention of spread, and management of clinical cases. The statement concludes that while progress has been made, more research is needed to improve vaccination and treatment strategies for EHV-1.The American College of Veterinary Internal Medicine (ACVIM) publishes consensus statements to provide up-to-date information on animal diseases. The updated consensus statement on equine herpesvirus-1 (EHV-1) addresses vaccination, treatment, diagnosis, and pathogenesis. The statement is based on systematic reviews and highlights the limitations of current evidence. Vaccination has limited effectiveness in preventing EHV-1 infection and disease, and pharmacologic treatments show minimal efficacy. Viremia is a key factor in the occurrence of abortion and EHM, but the relationship between viremia levels and disease outcomes is not fully understood. The best sampling strategy for EHV-1 detection involves testing both nasal secretions and blood, with nasal secretions being more effective in certain cases. The consensus statement also updates the 2009 statement, emphasizing the need for further research. The statement recommends vaccination as part of a biosecurity program, despite limited evidence of effectiveness. It also highlights the importance of early diagnosis, prevention of spread, and management of clinical cases. The statement concludes that while progress has been made, more research is needed to improve vaccination and treatment strategies for EHV-1.