The article discusses the current classification of chronic inflammatory enteropathies (CIEs) in dogs, which is based on clinical response to treatment trials, and proposes an updated classification. The current categories—food-responsive (FREs), antibiotic-responsive (AREs), immunosuppressant-responsive (IREs), and non-responsive enteropathies (NREs)—have been useful but are now challenged by recent research. The gut microbiota's role in CIEs has been highlighted, and the harmful effects of antibiotics on the microbiota have been noted. The authors propose replacing AREs with microbiota-related modulation-responsive enteropathies (MrMREs) to better reflect the importance of dietary changes and microbiota modulation. They also suggest that FREs may be more common than currently thought, as some NREs may respond to dietary trials. The article emphasizes the need for further research to validate these changes and to explore the best strategies for restoring a functional gut microbiota.The article discusses the current classification of chronic inflammatory enteropathies (CIEs) in dogs, which is based on clinical response to treatment trials, and proposes an updated classification. The current categories—food-responsive (FREs), antibiotic-responsive (AREs), immunosuppressant-responsive (IREs), and non-responsive enteropathies (NREs)—have been useful but are now challenged by recent research. The gut microbiota's role in CIEs has been highlighted, and the harmful effects of antibiotics on the microbiota have been noted. The authors propose replacing AREs with microbiota-related modulation-responsive enteropathies (MrMREs) to better reflect the importance of dietary changes and microbiota modulation. They also suggest that FREs may be more common than currently thought, as some NREs may respond to dietary trials. The article emphasizes the need for further research to validate these changes and to explore the best strategies for restoring a functional gut microbiota.