The article reviews the value-added utilization of crude glycerol, a byproduct of biodiesel production. Crude glycerol, produced in significant quantities due to the increasing demand for biodiesel, can be used as a feedstock for various value-added chemicals and animal feeds. The chemical composition of crude glycerol varies based on the production methods and feedstocks used, with impurities such as methanol, soap, catalysts, salts, and water being common. Despite these variations, crude glycerol has been found to be a good energy source for non-ruminant animals, improving feed performance and energy efficiency. Additionally, it can be converted into valuable chemicals through biological and conventional catalytic processes, including 1,3-propanediol, citric acid, poly(hydroxyalkanoates), butanol, hydrogen, and docosahexaenoic acid-rich algae. The article highlights the potential of crude glycerol in biorefineries and the need for further research to optimize its utilization, especially in terms of impurity management and cost-effectiveness.The article reviews the value-added utilization of crude glycerol, a byproduct of biodiesel production. Crude glycerol, produced in significant quantities due to the increasing demand for biodiesel, can be used as a feedstock for various value-added chemicals and animal feeds. The chemical composition of crude glycerol varies based on the production methods and feedstocks used, with impurities such as methanol, soap, catalysts, salts, and water being common. Despite these variations, crude glycerol has been found to be a good energy source for non-ruminant animals, improving feed performance and energy efficiency. Additionally, it can be converted into valuable chemicals through biological and conventional catalytic processes, including 1,3-propanediol, citric acid, poly(hydroxyalkanoates), butanol, hydrogen, and docosahexaenoic acid-rich algae. The article highlights the potential of crude glycerol in biorefineries and the need for further research to optimize its utilization, especially in terms of impurity management and cost-effectiveness.