Virtual reality (VR) is increasingly being used in motor rehabilitation to improve motor learning and functional recovery in patients with disabilities. This review discusses the current state of VR applications in motor rehabilitation, including the equipment used, the scientific rationale for its use, and the results of clinical studies. VR systems can provide immersive environments that allow patients to practice motor tasks in a controlled and engaging way. These systems can be used for a variety of rehabilitation purposes, including stroke rehabilitation, acquired brain injury, Parkinson’s disease, orthopedic rehabilitation, balance training, wheelchair mobility, and functional activities of daily living. The review also discusses the emerging field of telerehabilitation, which allows for remote rehabilitation sessions using VR technology. The review highlights four major findings from the studies: (1) people with disabilities can learn motor skills in VR; (2) movements learned in VR transfer to real-world tasks; (3) VR training can be more effective than real-world training in some cases; and (4) no cases of cybersickness have been reported in studies involving impaired populations. The review also discusses the equipment used in VR systems, including display devices, interface devices, and auditory input. It describes the scientific rationale for using VR in rehabilitation, including the importance of repetition, feedback, and motivation in motor learning. The review also discusses the neurophysiological processes involved in motor learning and how VR can enhance these processes. The review includes several studies that compare VR training to real-world training, showing that VR can be more effective in some cases. For example, a study on stroke patients showed that those who trained in VR improved more in motor tasks than those who trained in the real world. Another study on patients with stroke showed that VR training improved motor function, grip strength, and range of motion. The review also discusses the use of VR for upper extremity rehabilitation, including the development of VR systems that allow patients to practice motor tasks in a virtual environment. The review concludes that VR has the potential to be a powerful tool in motor rehabilitation, offering a way to provide repetitive practice, feedback, and motivation to improve motor function in patients with disabilities.Virtual reality (VR) is increasingly being used in motor rehabilitation to improve motor learning and functional recovery in patients with disabilities. This review discusses the current state of VR applications in motor rehabilitation, including the equipment used, the scientific rationale for its use, and the results of clinical studies. VR systems can provide immersive environments that allow patients to practice motor tasks in a controlled and engaging way. These systems can be used for a variety of rehabilitation purposes, including stroke rehabilitation, acquired brain injury, Parkinson’s disease, orthopedic rehabilitation, balance training, wheelchair mobility, and functional activities of daily living. The review also discusses the emerging field of telerehabilitation, which allows for remote rehabilitation sessions using VR technology. The review highlights four major findings from the studies: (1) people with disabilities can learn motor skills in VR; (2) movements learned in VR transfer to real-world tasks; (3) VR training can be more effective than real-world training in some cases; and (4) no cases of cybersickness have been reported in studies involving impaired populations. The review also discusses the equipment used in VR systems, including display devices, interface devices, and auditory input. It describes the scientific rationale for using VR in rehabilitation, including the importance of repetition, feedback, and motivation in motor learning. The review also discusses the neurophysiological processes involved in motor learning and how VR can enhance these processes. The review includes several studies that compare VR training to real-world training, showing that VR can be more effective in some cases. For example, a study on stroke patients showed that those who trained in VR improved more in motor tasks than those who trained in the real world. Another study on patients with stroke showed that VR training improved motor function, grip strength, and range of motion. The review also discusses the use of VR for upper extremity rehabilitation, including the development of VR systems that allow patients to practice motor tasks in a virtual environment. The review concludes that VR has the potential to be a powerful tool in motor rehabilitation, offering a way to provide repetitive practice, feedback, and motivation to improve motor function in patients with disabilities.