Wearable biosensors for cardiovascular monitoring using nanomaterials are gaining attention due to their potential to provide real-time, continuous, and precise data for personalized healthcare. These sensors are crucial for early diagnosis and management of cardiovascular diseases (CVDs), which are a leading cause of death globally. The integration of nanomaterials into biosensor development has enhanced detection sensitivity, signal fidelity, and stability, enabling more accurate and reliable monitoring of cardiac activity, blood pressure, pulse wave velocity, and biomarkers. Nanomaterials, defined by their nanoscale dimensions (1–100 nm), offer unique properties that improve biosensor performance, such as high specific surface area, which allows for sensitive signal detection in small sample volumes. Recent advancements include bimetallic nickel-cobalt oxide/carbon composites with enhanced electromagnetic wave absorption and flexible, biocompatible polystyrene/multiwalled carbon nanotubes (PS/MWCNTs) films with high permittivity and low loss. These materials contribute to the development of lightweight, non-invasive, and user-friendly devices that can monitor cardiovascular health in real-world settings. The use of nanomaterials in biosensors also facilitates device miniaturization and the creation of robust sensing probes, enabling continuous monitoring and proactive health management. The convergence of nanotechnology with biosensor development is revolutionizing cardiovascular health management, offering new possibilities for early detection, continuous monitoring, and improved patient outcomes. This review highlights the latest advancements in wearable biosensors for cardiovascular monitoring, focusing on the integration of nanomaterials, their fabrication, applications, and clinical implications. It also discusses the challenges and future prospects of nanomaterial-based wearable biosensors in cardiovascular healthcare.Wearable biosensors for cardiovascular monitoring using nanomaterials are gaining attention due to their potential to provide real-time, continuous, and precise data for personalized healthcare. These sensors are crucial for early diagnosis and management of cardiovascular diseases (CVDs), which are a leading cause of death globally. The integration of nanomaterials into biosensor development has enhanced detection sensitivity, signal fidelity, and stability, enabling more accurate and reliable monitoring of cardiac activity, blood pressure, pulse wave velocity, and biomarkers. Nanomaterials, defined by their nanoscale dimensions (1–100 nm), offer unique properties that improve biosensor performance, such as high specific surface area, which allows for sensitive signal detection in small sample volumes. Recent advancements include bimetallic nickel-cobalt oxide/carbon composites with enhanced electromagnetic wave absorption and flexible, biocompatible polystyrene/multiwalled carbon nanotubes (PS/MWCNTs) films with high permittivity and low loss. These materials contribute to the development of lightweight, non-invasive, and user-friendly devices that can monitor cardiovascular health in real-world settings. The use of nanomaterials in biosensors also facilitates device miniaturization and the creation of robust sensing probes, enabling continuous monitoring and proactive health management. The convergence of nanotechnology with biosensor development is revolutionizing cardiovascular health management, offering new possibilities for early detection, continuous monitoring, and improved patient outcomes. This review highlights the latest advancements in wearable biosensors for cardiovascular monitoring, focusing on the integration of nanomaterials, their fabrication, applications, and clinical implications. It also discusses the challenges and future prospects of nanomaterial-based wearable biosensors in cardiovascular healthcare.