This review discusses the advancements in wearable biosensors for cardiovascular monitoring, emphasizing the integration of nanomaterials. The shift towards home-based and personalized monitoring paradigms in healthcare, particularly for cardiovascular conditions, highlights the need for precise, real-time, and continuous data collection. Nanomaterials, with their unique properties, enhance the sensitivity, signal fidelity, and stability of biosensors, making them ideal for early diagnosis and management of critical health conditions. The review covers the latest developments in materials, design principles, functional mechanisms, and applications in monitoring cardiac activity, blood pressure, pulse wave velocity, and biomarker detection. It also discusses the challenges and prospects of nanomaterial-based wearable biosensors, highlighting their potential to revolutionize cardiovascular health management through early detection, continuous monitoring, and improved patient care.This review discusses the advancements in wearable biosensors for cardiovascular monitoring, emphasizing the integration of nanomaterials. The shift towards home-based and personalized monitoring paradigms in healthcare, particularly for cardiovascular conditions, highlights the need for precise, real-time, and continuous data collection. Nanomaterials, with their unique properties, enhance the sensitivity, signal fidelity, and stability of biosensors, making them ideal for early diagnosis and management of critical health conditions. The review covers the latest developments in materials, design principles, functional mechanisms, and applications in monitoring cardiac activity, blood pressure, pulse wave velocity, and biomarker detection. It also discusses the challenges and prospects of nanomaterial-based wearable biosensors, highlighting their potential to revolutionize cardiovascular health management through early detection, continuous monitoring, and improved patient care.