What else should hemostatic materials do beyond hemostasis: A review

What else should hemostatic materials do beyond hemostasis: A review

2024 | Xinran Yang, Xiudan Wang, Xing Gao, Xiaoqin Guo, Shike Hou, Jie Shi, Qi Lv
The article reviews the development and application of hemostatic materials beyond their primary function of rapid hemostasis. It highlights the need for these materials to possess additional functions to meet practical requirements in different scenarios, such as positioning at deep and narrow wounds, resistance to high blood pressure and wound movement, easy removal after hemostasis, and sustained action when retained as dressings. The review discusses various strategies for improving hemostatic materials, including wet adhesion, self-pumping and magnetic field driving, mechanical interlocking, specific targeting, and bio-inspired design. It also addresses the stability of material structures, easy removal or degradation after hemostasis, and sustained action at the injury site. The article emphasizes the importance of these additional functions in enhancing the effectiveness and practicality of hemostatic materials, providing valuable references for future research and product development.The article reviews the development and application of hemostatic materials beyond their primary function of rapid hemostasis. It highlights the need for these materials to possess additional functions to meet practical requirements in different scenarios, such as positioning at deep and narrow wounds, resistance to high blood pressure and wound movement, easy removal after hemostasis, and sustained action when retained as dressings. The review discusses various strategies for improving hemostatic materials, including wet adhesion, self-pumping and magnetic field driving, mechanical interlocking, specific targeting, and bio-inspired design. It also addresses the stability of material structures, easy removal or degradation after hemostasis, and sustained action at the injury site. The article emphasizes the importance of these additional functions in enhancing the effectiveness and practicality of hemostatic materials, providing valuable references for future research and product development.
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