WormBase, a major repository for *Caenorhabditis elegans* and other nematode genomes, has been updated and transitioning to the Alliance of Genome Resources (Alliance) infrastructure. The article outlines the current state of WormBase, its goals, and the progress of moving its core infrastructure to the Alliance. WormBase has been a critical resource for researchers in *C. elegans*, other nematodes, and the broader biological community for over two decades. It provides genome annotation, knowledgebase, software, disease models, and bioinformatics tools, and is recognized as a Core Global Biodata Resource. The transition to the Alliance is driven by the need for improved infrastructure, sustainability, and shared resources. WormBase will continue to interact with the *C. elegans* community, develop new features, and curate key information. The Alliance provides a shared infrastructure that allows for standardized, facile services for comparing genes across model organisms. The current infrastructure of WormBase is being moved to the Alliance's graph database (Neo4j), which will be replaced by a PostgreSQL relational database in the long term. WormBase data types, including genes, alleles, models, gene expression annotations, disease models, phenotypes, and interactions, are being harmonized and migrated to the Alliance. The transition involves moving data from Neo4j to PostgreSQL, with the Alliance providing a more rapid propagation of information from curated knowledgebases to the website. The data currently in the Alliance Neo4j database includes a subset of WormBase data types, with ongoing harmonization of the remaining data types and properties. The Alliance is also developing new tools and features, such as a gene ontology viewer, a pathway viewer, and a new gene summary tool. The WormBase website will continue to be supported until the transition to the Alliance is complete. The Alliance is also working on harmonizing data across model organisms, including the integration of gene expression data, genetic pathways, and disease models. The transition to the Alliance is expected to enhance the functionality and accessibility of WormBase for the *C. elegans* community and other researchers. The data and code for WormBase and the Alliance are freely available for download and use.WormBase, a major repository for *Caenorhabditis elegans* and other nematode genomes, has been updated and transitioning to the Alliance of Genome Resources (Alliance) infrastructure. The article outlines the current state of WormBase, its goals, and the progress of moving its core infrastructure to the Alliance. WormBase has been a critical resource for researchers in *C. elegans*, other nematodes, and the broader biological community for over two decades. It provides genome annotation, knowledgebase, software, disease models, and bioinformatics tools, and is recognized as a Core Global Biodata Resource. The transition to the Alliance is driven by the need for improved infrastructure, sustainability, and shared resources. WormBase will continue to interact with the *C. elegans* community, develop new features, and curate key information. The Alliance provides a shared infrastructure that allows for standardized, facile services for comparing genes across model organisms. The current infrastructure of WormBase is being moved to the Alliance's graph database (Neo4j), which will be replaced by a PostgreSQL relational database in the long term. WormBase data types, including genes, alleles, models, gene expression annotations, disease models, phenotypes, and interactions, are being harmonized and migrated to the Alliance. The transition involves moving data from Neo4j to PostgreSQL, with the Alliance providing a more rapid propagation of information from curated knowledgebases to the website. The data currently in the Alliance Neo4j database includes a subset of WormBase data types, with ongoing harmonization of the remaining data types and properties. The Alliance is also developing new tools and features, such as a gene ontology viewer, a pathway viewer, and a new gene summary tool. The WormBase website will continue to be supported until the transition to the Alliance is complete. The Alliance is also working on harmonizing data across model organisms, including the integration of gene expression data, genetic pathways, and disease models. The transition to the Alliance is expected to enhance the functionality and accessibility of WormBase for the *C. elegans* community and other researchers. The data and code for WormBase and the Alliance are freely available for download and use.